TC HSD 21

Modify Date: 2024-01-04 03:41:30

TC HSD 21 Structure
TC HSD 21 structure
Common Name TC HSD 21
CAS Number 330203-01-5 Molecular Weight 422.32
Density N/A Boiling Point N/A
Molecular Formula C17H12BrNO3S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TC HSD 21


TC HSD 21 is a potent 17β-hydroxysteroid dehydrogenase type 3 (17β-HSD3) inhibitor with an IC50 of 14 nM. TC HSD 21 shows excellent selectivity over 17β-HSD isoenzymes and nuclear receptors[1].

 Names

Name 5-(3-bromo-4-hydroxybenzylidene)-3-(4-methoxyphenyl)-2-thioxo-1,3-thiazolidin-4-one

 TC HSD 21 Biological Activity

Description TC HSD 21 is a potent 17β-hydroxysteroid dehydrogenase type 3 (17β-HSD3) inhibitor with an IC50 of 14 nM. TC HSD 21 shows excellent selectivity over 17β-HSD isoenzymes and nuclear receptors[1].
Related Catalog
Target

IC50: 14 nM (17β-HSD3)[1]

References

[1]. Harada K,et al. Identification of oxazolidinediones and thiazolidinediones as potent 17β-hydroxysteroid dehydrogenase type 3 inhibitors. Bioorg Med Chem Lett. 2012 Jan 1;22(1):504-7.

 Chemical & Physical Properties

Molecular Formula C17H12BrNO3S2
Molecular Weight 422.32
Exact Mass 420.94400
PSA 107.16000
LogP 4.63410
Storage condition 2-8℃
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