3-(pyridin-2-ylmethylidene)-1H-indol-2-one
Modify Date: 2024-01-08 13:44:22
3-(pyridin-2-ylmethylidene)-1H-indol-2-one structure
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Common Name | 3-(pyridin-2-ylmethylidene)-1H-indol-2-one | ||
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| CAS Number | 3367-88-2 | Molecular Weight | 222.24200 | |
| Density | 1.291g/cm3 | Boiling Point | 457.2ºC at 760 mmHg | |
| Molecular Formula | C14H10N2O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 230.3ºC | |
Use of 3-(pyridin-2-ylmethylidene)-1H-indol-2-one(E/Z)-GSK-3β inhibitor 1 is a racemic compound of (E)-GSK-3β inhibitor 1 and (Z)-GSK-3β inhibitor 1 isomers. GSK-3β inhibitor 1 (compound 3a) is a glycogen synthase kinase 3β (GSK-3β) inhibitor and demonstrates high antidiabetic efficacy, with an IC50 of 4.9 nM[1]. |
| Name | (3E)-3-(pyridin-2-ylmethylidene)-1H-indol-2-one |
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| Description | (E/Z)-GSK-3β inhibitor 1 is a racemic compound of (E)-GSK-3β inhibitor 1 and (Z)-GSK-3β inhibitor 1 isomers. GSK-3β inhibitor 1 (compound 3a) is a glycogen synthase kinase 3β (GSK-3β) inhibitor and demonstrates high antidiabetic efficacy, with an IC50 of 4.9 nM[1]. |
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| Related Catalog | |
| References |
| Density | 1.291g/cm3 |
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| Boiling Point | 457.2ºC at 760 mmHg |
| Molecular Formula | C14H10N2O |
| Molecular Weight | 222.24200 |
| Flash Point | 230.3ºC |
| Exact Mass | 222.07900 |
| PSA | 41.99000 |
| LogP | 2.71230 |
| Index of Refraction | 1.693 |
| Hazard Codes | Xi |
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| HS Code | 2933790090 |
| HS Code | 2933790090 |
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| Summary | 2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0% |