3b-Hydroxy-5-cholenoic acid

Modify Date: 2024-01-06 18:47:39

3b-Hydroxy-5-cholenoic acid Structure
3b-Hydroxy-5-cholenoic acid structure
Common Name 3b-Hydroxy-5-cholenoic acid
CAS Number 5255-17-4 Molecular Weight 374.55700
Density 1.11 g/cm3 Boiling Point 522.8ºC at 760 mmHg
Molecular Formula C24H38O3 Melting Point 232ºC
MSDS USA Flash Point 284.1ºC

 Use of 3b-Hydroxy-5-cholenoic acid


3b-Hydroxy-5-cholenoic acid is a monohydroxy bile acid of endogenous origin and could be found in children with the syndrome of hepatic ductular hypoplasia.

 Names

Name 3beta-hydroxy-delta5-cholenic acid
Synonym More Synonyms

 3b-Hydroxy-5-cholenoic acid Biological Activity

Description 3b-Hydroxy-5-cholenoic acid is a monohydroxy bile acid of endogenous origin and could be found in children with the syndrome of hepatic ductular hypoplasia.
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. Back P, et al. Identification of 3 beta-hydroxy-5-cholenoic acid in human meconium. Hoppe Seylers Z Physiol Chem. 1973 Jan;354(1):83-9.

 Chemical & Physical Properties

Density 1.11 g/cm3
Boiling Point 522.8ºC at 760 mmHg
Melting Point 232ºC
Molecular Formula C24H38O3
Molecular Weight 374.55700
Flash Point 284.1ºC
Exact Mass 374.28200
PSA 57.53000
LogP 5.42720
Index of Refraction -39.5 ° (C=1, Dioxane)

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases 22-24/25
RIDADR NONH for all modes of transport
WGK Germany 3

 Synthetic Route

 Articles20

More Articles
Hepatic bile salt sulfotransferases in the rat: sulfation of 3 beta-hydroxy-5-cholenoate during development.

J. Pediatr. Gastroenterol. Nutr. 12(2) , 260-8, (1991)

Bile salt sulfotransferase (BSS) activity for the fetal bile acid, 3 beta-hydroxy-5-cholenoate, was first detected in the fetus at 18-19 days of gestation and was twofold greater than for glycolithoch...

Determination of 3 beta-hydroxy-5-cholen-24-oic acid and its sulfate in human serum by gas chromatography-mass spectrometry.

Steroids 44(1) , 47-55, (1984)

The glycine conjugate of 3 beta-hydroxy-5-cholen-24-oic acid and its sulfate labeled with deuterium at the C-2, -4, and -23 positions were synthesized. A highly sensitive and specific quantitative ass...

Unusual serum bile acid pattern in children with the syndrome of hepatic ductular hypoplasia.

Clin. Chim. Acta 145(3) , 289-96, (1985)

Fasting bile acids in serum of eight children with the syndrome of hepatic ductular hypoplasia were analyzed by gas chromatography. The children did not receive any kind of treatment during the month ...

 Synonyms

MFCD00069468
Cholenic acid
3b-Hydroxy-5-cholenoic acid
5-cholenic acid-3B-ol
5-CHOLENIC ACID-3BETA-OL
3β-Hydroxy-DELTA5-cholenic Acid