Eudesmin

Modify Date: 2025-08-24 17:01:09

Eudesmin structure	Common Name	Eudesmin
	CAS Number	526-06-7	Molecular Weight	386.438
	Density	1.2±0.1 g/cm3	Boiling Point	517.3±50.0 °C at 760 mmHg
	Molecular Formula	C₂₂H₂₆O₆	Melting Point	108.5-109.5℃
	MSDS	N/A	Flash Point	209.8±30.0 °C

Use of Eudesmin

Eudesmin ((-)-Eudesmin) impairs adipogenic differentiation via inhibition of S6K1 signaling pathway. Eudesmin possesses diverse therapeutic effects, including anti-tumor, anti-inflammatory, and anti-bacterial activities[1].

Name	1H,3H-Furo[3,4-c]furan, 1,4-bis(3,4-dimethoxyphenyl)tetrahydro-, (1.α.,3a.α.,4.α.,6a.α.)-(-)
Synonym	More Synonyms

Description	Eudesmin ((-)-Eudesmin) impairs adipogenic differentiation via inhibition of S6K1 signaling pathway. Eudesmin possesses diverse therapeutic effects, including anti-tumor, anti-inflammatory, and anti-bacterial activities[1].
Related Catalog	Research Areas >> Cancer Research Areas >> Infection Research Areas >> Inflammation/Immunology Research Areas >> Metabolic Disease Signaling Pathways >> MAPK/ERK Pathway >> Ribosomal S6 Kinase (RSK)
Target	S6K1[1]
In Vitro	Treatment of mesenchymal stem cells (MSCs) with Eudesmin (20, 40, and 80μM) disturbs adipogenesis via suppression of S6K1 signaling pathway. Eudesmin treatment inhibits activation and nuclear translocation of S6K1. S6K1-mediated phosphorylation of H2B at serine 36 (H2BS36p) is reduced upon Eudesmin treatment[1].
References	[1]. Ki Hong Nam, et al. Eudesmin Impairs Adipogenic Differentiation via Inhibition of S6K1 Signaling Pathway. Biochem Biophys Res Commun. 2018 Nov 10;505(4):1148-1153.

Density	1.2±0.1 g/cm3
Boiling Point	517.3±50.0 °C at 760 mmHg
Melting Point	108.5-109.5℃
Molecular Formula	C₂₂H₂₆O₆
Molecular Weight	386.438
Flash Point	209.8±30.0 °C
Exact Mass	386.172943
PSA	55.38000
LogP	3.08
Vapour Pressure	0.0±1.3 mmHg at 25°C
Index of Refraction	1.547
InChIKey	PEUUVVGQIVMSAW-UHFFFAOYSA-N
SMILES	COc1ccc(C2OCC3C(c4ccc(OC)c(OC)c4)OCC23)cc1OC
Storage condition	2-8°C

Eudesmin MSDS(Chinese)

Hazard Codes	Xn
Risk Phrases	22
Safety Phrases	36

Precursor 0
DownStream 3
CAS#:93-07-2 Veratric acid CAS#:3395-03-7 1,2-DIMETHOXY-4... CAS#:67560-68-3 Lariciresinol d...

Name: Antifungal activity against Phomopsis obscurans assessed as growth inhibition at 50 u...
Source: ChEMBL
Target: Phomopsis obscurans
External Id: CHEMBL3052906

Name: Antifungal activity against Colletotrichum acutatum assessed as growth inhibition at ...
Source: ChEMBL
Target: Colletotrichum acutatum
External Id: CHEMBL3052908

Name: Antifungal activity against Colletotrichum gloeosporioides assessed as growth inhibit...
Source: ChEMBL
Target: Colletotrichum gloeosporioides
External Id: CHEMBL3052909

Name: Antifungal activity against Diaporthe ampelina assessed as growth inhibition at 50 to...
Source: ChEMBL
Target: Diaporthe ampelina
External Id: CHEMBL3052910

Name: Antifungal activity against Colletotrichum fragariae assessed as growth inhibition at...
Source: ChEMBL
Target: Colletotrichum fragariae
External Id: CHEMBL3052911

Name: Antifungal activity against Phomopsis obscurans assessed as growth inhibition at 50 t...
Source: ChEMBL
Target: Phomopsis obscurans
External Id: CHEMBL3052912

Name: Antifungal activity against Fusarium oxysporum assessed as growth inhibition at 50 to...
Source: ChEMBL
Target: Fusarium oxysporum
External Id: CHEMBL3052913

Name: Antialgal activity against Planktothrix agardhii assessed as inhibition measured for ...
Source: ChEMBL
Target: Planktothrix agardhii
External Id: CHEMBL3052942

Name: Small-molecule inhibitors of ST2 (IL1RL1)
Source: 20881
Target: interleukin-1 receptor-like 1 isoform [homo sapiens]
External Id: ST2_IL33_Inhibitors_Primary_Screening_77700

Name: Inhibition of LPS-induced nitric oxide production in mouse RAW264.7 cells after 24 hr...
Source: ChEMBL
Target: RAW264.7
External Id: CHEMBL3611158

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Pinoresinol dimethyl ether

Eudesamin,Eudesmin

(1S,3aR,4S,6aR)-1,4-Bis(3,4-dimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan

(7S,7’S,8R,8’R)-eudesmin

(1S,3aR,4S,6aR)-1,4-bis(3,4-dimethoxyphenyl)-hexahydrofuro[3,4-c]furan

eudesmin

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Eudesmin
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

BioBioPha
China
Product Name: Eudesmin
Price: ￥2900.0/5mg
Purity: 98.0%
Delivery: 10 Day
Contact: Xueping-Zheng
Email: 1477035482@qq.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 1H,3H-Furo[3,4-c]furan,1,4-bis(3,4-dimethoxyphenyl)tetrahydro-, (1R,3aS,4R,6aS)-
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

naturewill
China
Product Name: Eudesmin
Price: ￥Inquiry/5mg ￥Inquiry/20mg ￥Inquiry/100mg ￥Inquiry/1g
Purity: 98.0%
Delivery: Inquiry
Contact: Bella
Email: 3157321941@qq.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Eudesmin
Price: ￥4000.0/5mg
Purity: 98.0%
Delivery: 3 Day
Contact: Liu jia
Email: 2130147988@qq.com

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MSDS

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Precursor & DownStream

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Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.