Eudesmin

Modify Date: 2024-01-08 18:11:42

Eudesmin structure	Common Name	Eudesmin
	CAS Number	526-06-7	Molecular Weight	386.438
	Density	1.2±0.1 g/cm3	Boiling Point	517.3±50.0 °C at 760 mmHg
	Molecular Formula	C₂₂H₂₆O₆	Melting Point	108.5-109.5℃
	MSDS	N/A	Flash Point	209.8±30.0 °C

Use of Eudesmin

Eudesmin ((-)-Eudesmin) impairs adipogenic differentiation via inhibition of S6K1 signaling pathway. Eudesmin possesses diverse therapeutic effects, including anti-tumor, anti-inflammatory, and anti-bacterial activities[1].

Name	1H,3H-Furo[3,4-c]furan, 1,4-bis(3,4-dimethoxyphenyl)tetrahydro-, (1.α.,3a.α.,4.α.,6a.α.)-(-)
Synonym	More Synonyms

Description	Eudesmin ((-)-Eudesmin) impairs adipogenic differentiation via inhibition of S6K1 signaling pathway. Eudesmin possesses diverse therapeutic effects, including anti-tumor, anti-inflammatory, and anti-bacterial activities[1].
Related Catalog	Research Areas >> Cancer Research Areas >> Infection Research Areas >> Inflammation/Immunology Research Areas >> Metabolic Disease Signaling Pathways >> MAPK/ERK Pathway >> Ribosomal S6 Kinase (RSK)
Target	S6K1[1]
In Vitro	Treatment of mesenchymal stem cells (MSCs) with Eudesmin (20, 40, and 80μM) disturbs adipogenesis via suppression of S6K1 signaling pathway. Eudesmin treatment inhibits activation and nuclear translocation of S6K1. S6K1-mediated phosphorylation of H2B at serine 36 (H2BS36p) is reduced upon Eudesmin treatment[1].
References	[1]. Ki Hong Nam, et al. Eudesmin Impairs Adipogenic Differentiation via Inhibition of S6K1 Signaling Pathway. Biochem Biophys Res Commun. 2018 Nov 10;505(4):1148-1153.

Density	1.2±0.1 g/cm3
Boiling Point	517.3±50.0 °C at 760 mmHg
Melting Point	108.5-109.5℃
Molecular Formula	C₂₂H₂₆O₆
Molecular Weight	386.438
Flash Point	209.8±30.0 °C
Exact Mass	386.172943
PSA	55.38000
LogP	3.08
Vapour Pressure	0.0±1.3 mmHg at 25°C
Index of Refraction	1.547
Storage condition	2-8°C