Syringic acid

Modify Date: 2024-01-02 09:40:40

Syringic acid Structure
Syringic acid structure
Common Name Syringic acid
CAS Number 530-57-4 Molecular Weight 198.173
Density 1.3±0.1 g/cm3 Boiling Point 379.5±42.0 °C at 760 mmHg
Molecular Formula C9H10O5 Melting Point 205-209 °C(lit.)
MSDS Chinese USA Flash Point 155.0±21.4 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of Syringic acid


Syringic acid is correlated with high antioxidant activity and inhibition of LDL oxidation.

 Names

Name syringic acid
Synonym More Synonyms

 Syringic acid Biological Activity

Description Syringic acid is correlated with high antioxidant activity and inhibition of LDL oxidation.
Related Catalog
Target

Human Endogenous Metabolite

In Vitro Syringic acid is a phenol present in some distilled alcohol beverages. It is also a product of microbial (gut) metabolism of anthocyanins and other polyphenols that have been consumed[1]. Research suggests that phenolics from wine may play a positive role against oxidation of low-density lipoprotein (LDL), which is a key step in the development of atherosclerosis. Syringic acid is correlated with high antioxidant activity and inhibition of LDL oxidation[2].
References

[1]. Forester SC, et al. Identification of Cabernet Sauvignon anthocyanin gut microflora metabolites. J Agric Food Chem. 2008 Oct 8;56(19):9299-304.

[2]. Kalkan Yildirim H, et al. Protection capacity against low-density lipoprotein oxidation and antioxidant potential of some organic and non-organic wines. Int J Food Sci Nutr. 2004 Aug;55(5):351-62.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 379.5±42.0 °C at 760 mmHg
Melting Point 205-209 °C(lit.)
Molecular Formula C9H10O5
Molecular Weight 198.173
Flash Point 155.0±21.4 °C
Exact Mass 198.052826
PSA 75.99000
LogP 1.13
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.566
Stability Stable. Incompatible with strong bases, strong oxidizing agents.
Water Solubility 5780 mg/L (25 ºC)

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DH2090000
CHEMICAL NAME :
Benzoic acid, 4-hydroxy-3,5-dimethoxy-
CAS REGISTRY NUMBER :
530-57-4
BEILSTEIN REFERENCE NO. :
2115262
LAST UPDATED :
199709
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C9-H10-O5
MOLECULAR WEIGHT :
198.19

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
Cytogenetic analysis
TEST SYSTEM :
Rodent - hamster Ovary
DOSE/DURATION :
3 gm/L
REFERENCE :
CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975- Volume(issue)/page/year: 14,251,1981

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36-S37/39
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS DH2090000
HS Code 29189090

 Synthetic Route

 Customs

HS Code 2918990090
Summary 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Articles73

More Articles
Development of antibodies for determination of alkylresorcinol metabolites in human urine and elucidation of ELISA cross-reactivity.

J. Immunol. Methods 413 , 12-24, (2014)

Alkylresorcinols (ARs) are amphiphilic phenolic lipids and their two main metabolites, 3-(3,5-dihydroxyphenyl)-propanoic acid (DHPPA) and 3,5-dihydroxybenzoic acid (DHBA), can be used as biomarkers of...

Effect of selected Saccharomyces cerevisiae yeast strains and different aging techniques on the polysaccharide and polyphenolic composition and sensorial characteristics of Cabernet Sauvignon red wines.

J. Sci. Food Agric. 95 , 2132-44, (2015)

The objective of this work was to study the effect of two Saccharomyces cerevisiae yeast strains with different capabilities of polysaccharide liberation during alcoholic fermentation in addition to s...

Comparison between ATR-IR, Raman, concatenated ATR-IR and Raman spectroscopy for the determination of total antioxidant capacity and total phenolic content of Chinese rice wine.

Food Chem. 194 , 671-9, (2015)

The application of attenuated total reflectance infrared spectroscopy (ATR-IR), Raman spectroscopy (RS) and combination of ATR-IR and RS for measurements of total antioxidant capacity (TAC) and total ...

 Synonyms

QVR DQ CO1 EO1
Gallic acid 3,5-dimethyl ether
Cedar acid
3,5-Dimethoxy-4-hydroxybenzoic acid
4-hydroxy-3,5-O-dimethylbenzoic acid
Benzoic acid, 4-hydroxy-3,5-dimethoxy-
4-Hydroxy-3,5-dimethoxybenzoic acid
Syringic acid
3,5-Dimethoxy-4-hydroxybenzoic acid 4-Hydroxy-3,5-dimethoxy-benzoic acid
Benzoic acid,4-hydroxy-3,5-dimethoxy
4-Hydroxy-3,5-dimethoxy-benzoic acid
3,5-Dimethoxy-4-hydroxybenzyl acid
EINECS 208-486-8
3,5-Dimethoxy-4-hydroxybenzoate
MFCD00002552
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