Oroxin A

Modify Date: 2024-01-04 19:52:36

Oroxin A Structure
Oroxin A structure
 Common Name Oroxin A
CAS Number 57396-78-8 Molecular Weight 432.378
Density 1.6±0.1 g/cm3 Boiling Point 784.0±60.0 °C at 760 mmHg
Molecular Formula C21H20O10 Melting Point N/A
MSDS N/A Flash Point 279.0±26.4 °C

 Use of Oroxin A


Oroxin A is the major component of an ethanol-water Oroxylum indicum (L.) Kurz (Bignoniaceae) seed extract (OISE), activates peroxisome proliferator-activated receptor γ (PPARγ) by docking into the PPARγ protein ligand-binding domain. Oroxin A exhibits an inhibitory activity against α-glucosidase and an antioxidant capacity[1]. Oroxin A exerts anti-breast cancer effects by inducing ER stress-mediated senescence[2].

 Names

Name 5,6-Dihydroxy-4-oxo-2-phenyl-4H-chromen-7-yl β-D-glucopyranoside
Synonym More Synonyms

 Oroxin A Biological Activity

Description Oroxin A is the major component of an ethanol-water Oroxylum indicum (L.) Kurz (Bignoniaceae) seed extract (OISE), activates peroxisome proliferator-activated receptor γ (PPARγ) by docking into the PPARγ protein ligand-binding domain. Oroxin A exhibits an inhibitory activity against α-glucosidase and an antioxidant capacity[1]. Oroxin A exerts anti-breast cancer effects by inducing ER stress-mediated senescence[2].
Related Catalog
In Vitro Oroxin A (0.5- 100 μM; 24 hours) significantly increases the PPARγ transcription level and exhibits the strongest activation with 50 μM in HEK-293t cells[1].
References

[1]. Sun W, et al. Oroxin A from Oroxylum indicum prevents the progression from prediabetes to diabetes in streptozotocin and high-fat diet induced mice. Phytomedicine. 2018 Jan 1;38:24-34.

[2]. He J, et al. Oroxin A inhibits breast cancer cell growth by inducing robust endoplasmic reticulum stress and senescence. Anticancer Drugs. 2016 Mar;27(3):204-15.

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 784.0±60.0 °C at 760 mmHg
Molecular Formula C21H20O10
Molecular Weight 432.378
Flash Point 279.0±26.4 °C
Exact Mass 432.105652
PSA 170.05000
LogP 0.47
Vapour Pressure 0.0±2.9 mmHg at 25°C
Index of Refraction 1.717
Storage condition -20℃

 Safety Information

Hazard Codes N

 Synthetic Route

4-oxo-2-phenyl-4H-1-benzopyran-5,6,7-triyl triacetate structure

4-oxo-2-phenyl-...

CAS#:67047-05-6

~%

Oroxin A Structure

Oroxin A

CAS#:57396-78-8

Literature: Mezey-Vandor, Gabriella; Farkas, Lorand; Kanzel, Ida; Nogradi, Mihaly Chemische Berichte, 1980 , vol. 113, # 5 p. 1945 - 1949
7-(benzyloxy)-4-oxo-2-phenyl-4H-1-benzopyran-5,6-diyl diacetate structure

7-(benzyloxy)-4...

CAS#:67047-06-7

~%

Oroxin A Structure

Oroxin A

CAS#:57396-78-8

Literature: Mezey-Vandor, Gabriella; Farkas, Lorand; Kanzel, Ida; Nogradi, Mihaly Chemische Berichte, 1980 , vol. 113, # 5 p. 1945 - 1949
5,6-Diacetoxy-7-hydroxyflavon-7-O-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosid) structure

5,6-Diacetoxy-7...

CAS#:74293-55-3

~%

Oroxin A Structure

Oroxin A

CAS#:57396-78-8

Literature: Mezey-Vandor, Gabriella; Farkas, Lorand; Kanzel, Ida; Nogradi, Mihaly Chemische Berichte, 1980 , vol. 113, # 5 p. 1945 - 1949
2,3,4,6-Tetra-O-acetyl-alpha-D-glucopyranosyl bromide structure

2,3,4,6-Tetra-O...

CAS#:572-09-8

~%

Oroxin A Structure

Oroxin A

CAS#:57396-78-8

Literature: Mezey-Vandor, Gabriella; Farkas, Lorand; Kanzel, Ida; Nogradi, Mihaly Chemische Berichte, 1980 , vol. 113, # 5 p. 1945 - 1949
5,6-Diacetoxy-7-hydroxyflavon structure

5,6-Diacetoxy-7...

CAS#:67047-07-8

~%

Oroxin A Structure

Oroxin A

CAS#:57396-78-8

Literature: Mezey-Vandor, Gabriella; Farkas, Lorand; Kanzel, Ida; Nogradi, Mihaly Chemische Berichte, 1980 , vol. 113, # 5 p. 1945 - 1949

 Synonyms

5,6-dihydroxyflavone-7-glucoside
B-Aethyl-boracycloheptan
5,6-Dihydroxy-4-oxo-2-phenyl-4H-chromen-7-yl β-D-glucopyranoside
1-ethyl-borepane
4H-1-Benzopyran-4-one, 7-(β-D-glucopyranosyloxy)-5,6-dihydroxy-2-phenyl-
baicalein-7-O-glucoside
Borepane,1-ethyl
Baicalein 7-b-D-glucopyranoside
Oroxin A
Top Suppliers:I want be here

Get all suppliers and price by the below link:

Oroxin A suppliers

Oroxin A price

Related Compounds: More...
Oroxin A
31567-75-6
Oroxin A
205640-90-0
Camellianin A
109232-77-1
lactococcin A
138860-83-0
maquiroside A
110187-24-1
actinoplanone A
115655-86-2
Influenza A virus-IN-4
2390067-58-8
S-[2-[3-[[(2R)-4-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethyl] (4E,7E,10E,13E,16E)-icosa-4,7,10,13,16-pentaenethioa
121935-04-4
Benzeneethanol, a-ethyl-
701-70-2
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1158522-08-7
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
940364-43-2
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
134104-43-1
1-(pyridin-3-yl)-1H-pyrazole-3-carboxylic acid
1014631-62-9
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
131615-57-1
Ethyl 4-(benzylamino)oxane-4-carboxylate
1184713-98-1
(4-Methyl-tetrahydro-furan-2-yl)-methanol
6906-52-1
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
930439-75-1
4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
1018584-77-4
6-Methyl-5,7-diazaspiro[3.4]oct-5-EN-8-one
1211594-73-8
Chemsrc provides Oroxin A(CAS#:57396-78-8) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Oroxin A are included as well.>> amp version: Oroxin A

Home | MSDS/SDS Database Search | Journals | Product Classification | Biologically Active Compounds | Selling Leads | About Us | Disclaimer

Copyright © 2024 ChemSrc All Rights Reserved