Bromo-PEG2-alcohol

Modify Date: 2024-01-03 18:58:43

Bromo-PEG2-alcohol Structure
Bromo-PEG2-alcohol structure
Common Name Bromo-PEG2-alcohol
CAS Number 57641-66-4 Molecular Weight 169.01700
Density 1.514±0.06 g/cm3 Boiling Point 228.9±15.0 °C
Molecular Formula C4H9BrO2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Bromo-PEG2-alcohol


Bromo-PEG2-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 2-(2-Bromoethoxy)ethanol
Synonym More Synonyms

 Bromo-PEG2-alcohol Biological Activity

Description Bromo-PEG2-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.514±0.06 g/cm3
Boiling Point 228.9±15.0 °C
Molecular Formula C4H9BrO2
Molecular Weight 169.01700
Exact Mass 167.97900
PSA 29.46000
LogP 0.39020

 Safety Information

Hazard Codes C

 Synthetic Route

~63%

Bromo-PEG2-alcohol Structure

Bromo-PEG2-alcohol

CAS#:57641-66-4

Literature: An, Haoyun; Bradshaw, Jerald S.; Krakowiak, Krzysztof E.; Tarbet, Bryon J.; Dalley, N. Kent; et al. Journal of Organic Chemistry, 1993 , vol. 58, # 27 p. 7694 - 7699

~%

Bromo-PEG2-alcohol Structure

Bromo-PEG2-alcohol

CAS#:57641-66-4

Literature: DE670419 , ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 25, p. 865

~%

Bromo-PEG2-alcohol Structure

Bromo-PEG2-alcohol

CAS#:57641-66-4

Literature: DE670419 , ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 25, p. 867

~%

Bromo-PEG2-alcohol Structure

Bromo-PEG2-alcohol

CAS#:57641-66-4

Literature: Annales de Chimie (Cachan, France), , vol. <3>67, p. 272

~%

Detail
Literature: Annales de Chimie (Cachan, France), , vol. <3>67, p. 272

 Synonyms

2-(2-bromoethoxy)benzoic aldehyde
2-(2'-bromoethoxy)ethanol
2'-Brom-2-hydroxy-diaethylaether
2-(2-Bromoethoxy)benzenecarbaldehyde
2-(2-Brom-aethoxy)-aethanol
2-(2-Brom-aethoxy)-benzaldehyd
o-(2-bromoethoxy)benzaldehyde
2-(2-bromo-ethoxy)-benzaldehyde
2<(1-formyl-2-phenyl)oxy>ethylbromide
2-bromoethoxyethanol
Bromo-PEG2-alcohol
Top Suppliers:I want be here


Get all suppliers and price by the below link:

Bromo-PEG2-alcohol suppliers

Bromo-PEG2-alcohol price