m-PEG7-thiol

Modify Date: 2024-01-02 14:44:11

m-PEG7-thiol Structure
m-PEG7-thiol structure
Common Name m-PEG7-thiol
CAS Number 651042-82-9 Molecular Weight 356.47500
Density 1.065 Boiling Point N/A
Molecular Formula C15H32O7S Melting Point N/A
MSDS Chinese USA Flash Point N/A

 Use of m-PEG7-thiol


m-PEG7-thiol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanethiol
Synonym More Synonyms

 m-PEG7-thiol Biological Activity

Description m-PEG7-thiol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Density 1.065
Molecular Formula C15H32O7S
Molecular Weight 356.47500
Exact Mass 356.18700
PSA 103.41000
LogP 0.66220
Storage condition -20°C

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport

 Articles1

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 Synonyms

O-(2-Mercaptoethyl)-O inverted exclamation marka-methyl-hexa(ethylene glycol)
AmbotzPEG1167
mPEG thiol
2,5,8,11,14,17,20-HEPTAOXADOCOSANE-22-THIOL
O-(2-Mercaptoethyl)-O'-methyl-hexa(ethylene glycol)
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