m-PEG7-Tos

Modify Date: 2024-01-05 09:10:17

m-PEG7-Tos Structure
m-PEG7-Tos structure
Common Name m-PEG7-Tos
CAS Number 79622-11-0 Molecular Weight 494.59600
Density N/A Boiling Point N/A
Molecular Formula C22H38O10S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of m-PEG7-Tos


m-PEG7-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name mPEG7-OTs
Synonym More Synonyms

 m-PEG7-Tos Biological Activity

Description m-PEG7-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C22H38O10S
Molecular Weight 494.59600
Exact Mass 494.21900
PSA 116.36000
LogP 2.52710

 Precursor & DownStream

Precursor  0

DownStream  2

 Synonyms

MFCD21363273
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