m-PEG7-NHS ester

Modify Date: 2024-01-15 21:58:42

m-PEG7-NHS ester Structure
m-PEG7-NHS ester structure
Common Name m-PEG7-NHS ester
CAS Number 874208-92-1 Molecular Weight 465.49200
Density N/A Boiling Point N/A
Molecular Formula C20H35NO11 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of m-PEG7-NHS ester


m-PEG7-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

 Names

Name 3-{2-[2-(2-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-propionic acid 2,5-dioxo-pyrrolidin-1-yl ester
Synonym More Synonyms

 m-PEG7-NHS ester Biological Activity

Description m-PEG7-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
Related Catalog
In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References

[1]. Lepage ML, et al. Design, synthesis and photochemical properties of the first examples of iminosugar clustersbased on fluorescent cores. Beilstein J Org Chem. 2015 May 6;11:659-67.

 Chemical & Physical Properties

Molecular Formula C20H35NO11
Molecular Weight 465.49200
Exact Mass 465.22100
PSA 128.29000

 Safety Information

Hazard Codes Xi

 Synonyms

m-peg7-nhs ester
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