GSK 264220A

Modify Date: 2024-01-08 12:09:49

GSK 264220A Structure
GSK 264220A structure
Common Name GSK 264220A
CAS Number 685506-42-7 Molecular Weight 363.431
Density 1.4±0.1 g/cm3 Boiling Point N/A
Molecular Formula C17H21N3O4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of GSK 264220A


GSK264220A is a potent endothelial lipase inhibitor with IC50 of 16 nM. GSK264220A has the potential to decrease the risk of cardiovascular disease[1].

 Names

Name 1-(2-methyl-5-piperidin-1-ylsulfonylfuran-3-yl)-3-phenylurea
Synonym More Synonyms

 GSK 264220A Biological Activity

Description GSK264220A is a potent endothelial lipase inhibitor with IC50 of 16 nM. GSK264220A has the potential to decrease the risk of cardiovascular disease[1].
Related Catalog
References

[1]. Keller PM, et al. A high-throughput screen for endothelial lipase using HDL as substrate. J Biomol Screen. 2008 Jul;13(6):468-75.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Molecular Formula C17H21N3O4S
Molecular Weight 363.431
Exact Mass 363.125275
PSA 100.03000
LogP 2.01
Index of Refraction 1.633

 Precursor & DownStream

Precursor  1

DownStream  0

 Synonyms

Urea, N-[2-methyl-5-(1-piperidinylsulfonyl)-3-furanyl]-N'-phenyl-
1-[2-Methyl-5-(1-piperidinylsulfonyl)-3-furyl]-3-phenylurea
1-[2-Methyl-5-(piperidin-1-ylsulfonyl)-3-furyl]-3-phenylurea
N-[2-methyl-5-(piperidinosulfonyl)-3-furyl]-N'-phenylurea
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