GSK 264220A

Modify Date: 2024-01-08 12:09:49

GSK 264220A structure	Common Name	GSK 264220A
	CAS Number	685506-42-7	Molecular Weight	363.431
	Density	1.4±0.1 g/cm3	Boiling Point	N/A
	Molecular Formula	C₁₇H₂₁N₃O₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of GSK 264220A

GSK264220A is a potent endothelial lipase inhibitor with IC50 of 16 nM. GSK264220A has the potential to decrease the risk of cardiovascular disease[1].

Name	1-(2-methyl-5-piperidin-1-ylsulfonylfuran-3-yl)-3-phenylurea
Synonym	More Synonyms

Description	GSK264220A is a potent endothelial lipase inhibitor with IC50 of 16 nM. GSK264220A has the potential to decrease the risk of cardiovascular disease[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Others >> Others
References	[1]. Keller PM, et al. A high-throughput screen for endothelial lipase using HDL as substrate. J Biomol Screen. 2008 Jul;13(6):468-75.

Density	1.4±0.1 g/cm3
Molecular Formula	C₁₇H₂₁N₃O₄S
Molecular Weight	363.431
Exact Mass	363.125275
PSA	100.03000
LogP	2.01
Index of Refraction	1.633

2-METHYL-5-(PIPERIDINOSULFONYL)-3-FUROIC ACID structure

2-METHYL-5-(PIP...

CAS#:306936-38-9

structure

CAS#:74497-02-2

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2-methyl-N-phenyl-5-(piperidin-1-ylsulfonyl)furan-3-carboxamide structure

2-methyl-N-phen...

CAS#:681428-74-0

GSK 264220A Structure

GSK 264220A

CAS#:685506-42-7

Literature: Goodman, Krista B.; Bury, Michael J.; Cheung, Mui; Cichy-Knight, Maria A.; Dowdell, Sarah E.; Dunn, Allison K.; Lee, Dennis; Lieby, Jeffrey A.; Moore, Michael L.; Scherzer, Daryl A.; Sha, Deyou; Suarez, Dominic P.; Murphy, Dennis J.; Harpel, Mark R.; Manas, Eric S.; McNulty, Dean E.; Annan, Roland S.; Matico, Rosalie E.; Schwartz, Benjamin K.; Trill, John J.; Sweitzer, Thomas D.; Wang, Da-yuan; Keller, Paul M.; Krawiec, John A.; Jaye, Michael C. Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 1 p. 27 - 30

Precursor 1
CAS#:306936-38-9 2-METHYL-5-(PIP...
DownStream 0

Urea, N-[2-methyl-5-(1-piperidinylsulfonyl)-3-furanyl]-N'-phenyl-

1-[2-Methyl-5-(1-piperidinylsulfonyl)-3-furyl]-3-phenylurea

1-[2-Methyl-5-(piperidin-1-ylsulfonyl)-3-furyl]-3-phenylurea

N-[2-methyl-5-(piperidinosulfonyl)-3-furyl]-N'-phenylurea

DC Chemicals Limited
China
Product Name: GSK-264220A
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: N-[2-Methyl-5-(1-piperidinylsulfonyl)-3-furanyl]-N'-phenylurea
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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