Dimethylamino-PEG2-C2-NH2

Modify Date: 2024-01-09 07:38:30

Dimethylamino-PEG2-C2-NH2 Structure
Dimethylamino-PEG2-C2-NH2 structure
Common Name Dimethylamino-PEG2-C2-NH2
CAS Number 692782-62-0 Molecular Weight 176.26
Density N/A Boiling Point N/A
Molecular Formula C8H20N2O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Dimethylamino-PEG2-C2-NH2


Dimethylamino-PEG2-C2-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Dimethylamino-PEG2-C2-NH2

 Dimethylamino-PEG2-C2-NH2 Biological Activity

Description Dimethylamino-PEG2-C2-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C8H20N2O2
Molecular Weight 176.26