Thalidomide-NH-PEG2-C2-NH2 TFA

Modify Date: 2024-01-09 22:14:31

Thalidomide-NH-PEG2-C2-NH2 TFA Structure
Thalidomide-NH-PEG2-C2-NH2 TFA structure
Common Name Thalidomide-NH-PEG2-C2-NH2 TFA
CAS Number 2097509-36-7 Molecular Weight 518.44
Density N/A Boiling Point N/A
Molecular Formula C21H25F3N4O8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Thalidomide-NH-PEG2-C2-NH2 TFA


Thalidomide-O-amido-PEG3-C2-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology[1].

 Names

Name Thalidomide-NH-PEG2-C2-NH2 TFA

 Thalidomide-NH-PEG2-C2-NH2 TFA Biological Activity

Description Thalidomide-O-amido-PEG3-C2-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology[1].
Related Catalog
References

[1]. Wang Z, et al. Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Target Binding Ligands. J Med Chem. 2019 Sep 12;62(17):8152-8163.

 Chemical & Physical Properties

Molecular Formula C21H25F3N4O8
Molecular Weight 518.44

 Safety Information

Hazard Codes Xi
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