Thalidomide-NH-PEG2-C2-NH2

Modify Date: 2024-04-05 05:45:15

Thalidomide-NH-PEG2-C2-NH2 Structure
Thalidomide-NH-PEG2-C2-NH2 structure
Common Name Thalidomide-NH-PEG2-C2-NH2
CAS Number 2093416-32-9 Molecular Weight 404.42
Density N/A Boiling Point N/A
Molecular Formula C19H24N4O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Thalidomide-NH-PEG2-C2-NH2


Thalidomide-O-amido-PEG3-C2-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology[1].

 Names

Name Thalidomide-NH-PEG2-C2-NH2

 Thalidomide-NH-PEG2-C2-NH2 Biological Activity

Description Thalidomide-O-amido-PEG3-C2-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology[1].
Related Catalog
References

[1]. Wang Z, et al. Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Target Binding Ligands. J Med Chem. 2019 Sep 12;62(17):8152-8163.

 Chemical & Physical Properties

Molecular Formula C19H24N4O6
Molecular Weight 404.42

 Safety Information

Hazard Codes Xi
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