SUVN-502

Modify Date: 2024-01-30 00:23:33

SUVN-502 Structure
SUVN-502 structure
 Common Name SUVN-502
CAS Number 701205-60-9 Molecular Weight 478.40
Density N/A Boiling Point N/A
Molecular Formula C21H24BrN3O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of SUVN-502


Masupirdine free base (SUVN-502 free base) is a potent, selective, orally bioavailable, and brain penetrant 5-HT6 receptor antagonist (Ki of 2.04 nM for human 5-HT6 receptor). Masupirdine free base (SUVN-502 free base) shows high selectivity over 5-HT2A receptor and other 100 target sites, and has potential for treatment of Alzheimer's disease[1].

 Names

Name Masupirdine free base

 SUVN-502 Biological Activity

Description Masupirdine free base (SUVN-502 free base) is a potent, selective, orally bioavailable, and brain penetrant 5-HT6 receptor antagonist (Ki of 2.04 nM for human 5-HT6 receptor). Masupirdine free base (SUVN-502 free base) shows high selectivity over 5-HT2A receptor and other 100 target sites, and has potential for treatment of Alzheimer's disease[1].
Related Catalog
Target

Ki: 2.04 nM (human 5-HT6 receptor)[1]

References

[1]. Nirogi R, et al. Discovery and Development of 1-[(2-Bromophenyl)sulfonyl]-5-methoxy-3-[(4-methyl-1-piperazinyl)methyl]-1H-indole Dimesylate Monohydrate (SUVN-502): A Novel, Potent, Selective and Orally Active Serotonin 6 (5-HT6) Receptor Antagonist for Potential Treatment of Alzheimer's Disease. J Med Chem. 2017 Mar 9;60(5):1843-1859.

 Chemical & Physical Properties

Molecular Formula C21H24BrN3O3S
Molecular Weight 478.40
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Chemsrc provides SUVN-502(CAS#:701205-60-9) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of SUVN-502 are included as well.>> amp version: SUVN-502

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