Rac1-IN-6

Modify Date: 2023-01-14 16:17:07

Rac1-IN-6 structure	Common Name	Rac1-IN-6
	CAS Number	701223-06-5	Molecular Weight	388.485
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₃H₂₀N₂O₂S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Rac1-IN-6

A novel selective small molecule Rac1 inhibitor that blocks Rac1-PAK1 complex formation with IC50 of 88±48 nM; diminishes the EGF-induced Rac1 activation in CD18/HPAF cells with EC50 of 22.4±3.2 uM, has no inhibitory effect on either Cdc42 or RhoA in CD18/HPAF cells; inhibits the proliferation, reduces migration of pancreatic cancer cells.

Name	Rac1-IN-6

Description	A novel selective small molecule Rac1 inhibitor that blocks Rac1-PAK1 complex formation with IC50 of 88±48 nM; diminishes the EGF-induced Rac1 activation in CD18/HPAF cells with EC50 of 22.4±3.2 uM, has no inhibitory effect on either Cdc42 or RhoA in CD18/HPAF cells; inhibits the proliferation, reduces migration of pancreatic cancer cells.
References	References 1. Arnst JL, et al. Oncotarget. 2017 May 23;8(21):34586-34600. View Related Products by Target Small GTPase

Molecular Formula	C₂₃H₂₀N₂O₂S
Molecular Weight	388.485

DC Chemicals Limited
China
Product Name: Rac1-IN-6
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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