Thiol-C9-PEG4-acid

Modify Date: 2024-01-16 17:41:15

Thiol-C9-PEG4-acid Structure
Thiol-C9-PEG4-acid structure
Common Name Thiol-C9-PEG4-acid
CAS Number 716339-41-2 Molecular Weight 394.57
Density N/A Boiling Point N/A
Molecular Formula C19H38O6S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Thiol-C9-PEG4-acid


Thiol-C9-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Thiol-C9-PEG4-acid

 Thiol-C9-PEG4-acid Biological Activity

Description Thiol-C9-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C19H38O6S
Molecular Weight 394.57