Thiol-C9-PEG7

Modify Date: 2024-01-04 12:53:28

Thiol-C9-PEG7 Structure
Thiol-C9-PEG7 structure
Common Name Thiol-C9-PEG7
CAS Number 130727-44-5 Molecular Weight 468.68800
Density 1.023g/cm3 Boiling Point 550.4ºC at 760mmHg
Molecular Formula C23H48O7S Melting Point N/A
MSDS Chinese USA Flash Point 286.7ºC

 Use of Thiol-C9-PEG7


Thiol-C9-PEG7 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 2-[2-[2-[2-[2-[2-(11-sulfanylundecoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
Synonym More Synonyms

 Thiol-C9-PEG7 Biological Activity

Description Thiol-C9-PEG7 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.023g/cm3
Boiling Point 550.4ºC at 760mmHg
Molecular Formula C23H48O7S
Molecular Weight 468.68800
Flash Point 286.7ºC
Exact Mass 468.31200
PSA 114.41000
LogP 3.51900
Vapour Pressure 0mmHg at 25°C
Index of Refraction n20/D 1.474

 Safety Information

RIDADR NONH for all modes of transport

 Synonyms

MUHEG
3,6,9,12,15,18-Hexaoxanonacosan-1-ol,29-mercapto
Thiol-C9-PEG7
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