Methyl-PEG3-bromide
Modify Date: 2024-01-01 22:23:35
Methyl-PEG3-bromide structure
|
Common Name | Methyl-PEG3-bromide | ||
|---|---|---|---|---|
| CAS Number | 72593-77-2 | Molecular Weight | 227.09600 | |
| Density | 1.288g/cm3 | Boiling Point | 245.798ºC at 760 mmHg | |
| Molecular Formula | C7H15BrO3 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 96.375ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of Methyl-PEG3-bromideMethyl-PEG3-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
| Name | Diethylene Glycol 2-Bromoethyl Methyl Ether |
|---|---|
| Synonym | More Synonyms |
| Description | Methyl-PEG3-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.288g/cm3 |
|---|---|
| Boiling Point | 245.798ºC at 760 mmHg |
| Molecular Formula | C7H15BrO3 |
| Molecular Weight | 227.09600 |
| Flash Point | 96.375ºC |
| Exact Mass | 226.02000 |
| PSA | 27.69000 |
| LogP | 1.06090 |
| Index of Refraction | 1.451 |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P280-P304 + P340 + P312-P305 + P351 + P338-P337 + P313 |
| RIDADR | NONH for all modes of transport |
|
~86%
Methyl-PEG3-bromide CAS#:72593-77-2 |
| Literature: Karimi, Babak; Mansouri, Fariborz; Vali, Hojatollah Green Chemistry, 2014 , vol. 16, # 5 p. 2587 - 2596 |
|
~67%
Methyl-PEG3-bromide CAS#:72593-77-2 |
| Literature: Wakim, Salem; Bouchard, Jimmy; Blouin, Nicolas; Michaud, Alexandre; Leclerc, Mario Organic Letters, 2004 , vol. 6, # 19 p. 3413 - 3416 |
|
~93%
Methyl-PEG3-bromide CAS#:72593-77-2 |
| Literature: Schou, Ole; Larsen, Per Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1981 , vol. 35, # 5 p. 337 - 340 |
CAS#:6048-68-6
CAS#:31521-83-2| 1-[2-(2-bromoethoxy)ethoxy]-2-methoxyethane |