Ms-PEG2-Ms

Modify Date: 2024-01-06 07:48:37

Use of Ms-PEG2-Ms

Ms-PEG2-Ms is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	2-(2-methylsulfonyloxyethoxy)ethyl methanesulfonate
Synonym	More Synonyms

Description	Ms-PEG2-Ms is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Hazard Codes	T+
HS Code	2904100000

Methanesulfonyl...

CAS#:124-63-0

Diethylene glycol

CAS#:111-46-6

~94%

Ms-PEG2-Ms

CAS#:34604-52-9

Precursor 2
CAS#:124-63-0 Methanesulfonyl... CAS#:111-46-6 Diethylene glycol
DownStream 10
CAS#:34270-90-1 2-IODOETHYL ETHER CAS#:92-53-5 4-Phenylmorpholine CAS#:39910-98-0 4-Morpholinoace... CAS#:19614-15-4 ETHYL 4-MORPHOL...
CAS#:24345-74-2 Azido-PEG1-azide CAS#:5414-19-7 Bis(2-bromoethy... CAS#:10282-31-2 4-Morpholinoben... CAS#:10389-51-2 4-(4-nitropheny...
CAS#:14262-60-3 Dibenzo-15-crow... CAS#:3077-16-5 4-(P-TOLYL)MORP...

HS Code	2904100000
Summary	2904100000 derivatives containing only sulpho groups, their salts and ethyl esters。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

oxydiethane-2,1-diyl dimethanesulfonate

diethyleneglycol bis-methane-sulfonyl ester

dimethyl 3-oxapentane-1,5-disulfonate

di-mesyl-diglyme

Diethylene Glycol Dimesylate

2,2'-Oxybis-ethanol Dimethanesulfonate

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