Diethylene glycol bis(p-toluenesulfonate) structure
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Common Name | Diethylene glycol bis(p-toluenesulfonate) | ||
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CAS Number | 7460-82-4 | Molecular Weight | 414.493 | |
Density | 1.3±0.1 g/cm3 | Boiling Point | 581.2±45.0 °C at 760 mmHg | |
Molecular Formula | C18H22O7S2 | Melting Point | 87-89 °C(lit.) | |
MSDS | Chinese USA | Flash Point | 305.3±28.7 °C | |
Symbol |
GHS07 |
Signal Word | Warning |
Use of Diethylene glycol bis(p-toluenesulfonate)Diethylene glycol bis(p-toluenesulfonate) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
Name | Oxybis(ethane-2,1-diyl) bis(4-methylbenzenesulfonate) |
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Synonym | More Synonyms |
Description | Diethylene glycol bis(p-toluenesulfonate) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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Related Catalog | |
Target |
PEGs |
In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
References |
Density | 1.3±0.1 g/cm3 |
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Boiling Point | 581.2±45.0 °C at 760 mmHg |
Melting Point | 87-89 °C(lit.) |
Molecular Formula | C18H22O7S2 |
Molecular Weight | 414.493 |
Flash Point | 305.3±28.7 °C |
Exact Mass | 414.080688 |
PSA | 112.73000 |
LogP | 2.70 |
Vapour Pressure | 0.0±1.6 mmHg at 25°C |
Index of Refraction | 1.554 |
Symbol |
GHS07 |
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Signal Word | Warning |
Hazard Statements | H315-H319-H335 |
Precautionary Statements | P261-P305 + P351 + P338 |
Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
Hazard Codes | Xi: Irritant; |
Risk Phrases | R36/37/38 |
Safety Phrases | S26-S36 |
RIDADR | NONH for all modes of transport |
WGK Germany | 3 |
HS Code | 2904100000 |
HS Code | 2904100000 |
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Summary | 2904100000 derivatives containing only sulpho groups, their salts and ethyl esters。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0% |
Synthesis of new benzosulfoxide macrocyclic compounds. Shockravi A, et al.
Phosphorus. Sulfur. Silicon Relat. Elem. 179(3) , 535-41, (2004)
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Ethanol, 2,2'-oxybis-, bis(4-methylbenzenesulfonate) |
Oxydi-2,1-ethanediyl bis(4-methylbenzenesulfonate) |
oxydiethane-2,1-diyl bis(4-methylbenzenesulfonate) |
MFCD00026001 |
2-[2-(4-methylphenyl)sulfonyloxyethoxy]ethyl 4-methylbenzenesulfonate |