Tos-PEG2-OH structure
|
Common Name | Tos-PEG2-OH | ||
---|---|---|---|---|
CAS Number | 118591-58-5 | Molecular Weight | 260.30700 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C11H16O5S | Melting Point | N/A | |
MSDS | USA | Flash Point | N/A |
Use of Tos-PEG2-OHTos-PEG2-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
Name | 2-(2-Hydroxyethoxy)ethyl 4-methylbenzenesulfonate |
---|---|
Synonym | More Synonyms |
Description | Tos-PEG2-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
---|---|
Related Catalog | |
Target |
PEGs |
In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
References |
Molecular Formula | C11H16O5S |
---|---|
Molecular Weight | 260.30700 |
Exact Mass | 260.07200 |
PSA | 81.21000 |
LogP | 1.79000 |
Hazard Codes | Xn |
---|---|
HS Code | 2909499000 |
~97% Tos-PEG2-OH CAS#:118591-58-5 |
Literature: NATIONAL UNIVERSITY OF IRELAND, GALWAY Patent: US2011/217750 A1, 2011 ; Location in patent: Page/Page column 19 ; |
~% Tos-PEG2-OH CAS#:118591-58-5 |
Literature: Song, Rita; Kim, Yeong-Sang; Lee, Chong Ock; Sohn, Youn Soo Tetrahedron Letters, 2003 , vol. 44, # 8 p. 1537 - 1540 |
HS Code | 2909499000 |
---|---|
Summary | 2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0% |
2-(2-hydroxyethoxy)ethyl p-methylbenzenesulfonate |
2-(2-hydroxyethoxy)ethyl 4-methyl benzenesulfonate |
toluene-4-sulfonic acid 2-(2-hydroxyethoxy)ethyl ester |
2-(2-{[(4-methylbenzene)sulfonyl]oxy}ethoxy)ethan-1-ol |
diethylene glycol mono-p-toluenesulfonate |
Ts(OCH2CH2)2OH |
Ethanol,2-(2-hydroxyethoxy)-,1-(4-Methylbenzenesulfonate) |