Xanthoxylin

Modify Date: 2024-01-04 21:54:00

Xanthoxylin structure	Common Name	Xanthoxylin
	CAS Number	90-24-4	Molecular Weight	196.200
	Density	1.2±0.1 g/cm3	Boiling Point	355.1±37.0 °C at 760 mmHg
	Molecular Formula	C₁₀H₁₂O₄	Melting Point	80-84 °C(lit.)
	MSDS	Chinese USA	Flash Point	141.2±20.0 °C

Use of Xanthoxylin

Xanthoxylin (Xanthoxyline) is isolated from Zanthoxylum simulans. Xanthoxylin (Xanthoxyline) has antifungal and antispasmodic activities[1][2].

Name	4',6'-Dimethoxy-2'-hydroxyacetophenone
Synonym	More Synonyms

Description	Xanthoxylin (Xanthoxyline) is isolated from Zanthoxylum simulans. Xanthoxylin (Xanthoxyline) has antifungal and antispasmodic activities[1][2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal
References	[1]. Cechinel Filho V, et al. Antispasmodic activity of xanthoxyline derivatives: structure-activity relationships.J Pharm Sci. 1995 Apr;84(4):473-5. [2]. Pinheiro TR, et al. In vitro antifungal evaluation and studies on the mode of action of xanthoxyline derivatives.Arzneimittelforschung. 1999 Dec;49(12):1039-43.

Description

Xanthoxylin (Xanthoxyline) is isolated from Zanthoxylum simulans. Xanthoxylin (Xanthoxyline) has antifungal and antispasmodic activities[1][2].

Related Catalog

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Fungal

References

[1]. Cechinel Filho V, et al. Antispasmodic activity of xanthoxyline derivatives: structure-activity relationships.J Pharm Sci. 1995 Apr;84(4):473-5.

[2]. Pinheiro TR, et al. In vitro antifungal evaluation and studies on the mode of action of xanthoxyline derivatives.Arzneimittelforschung. 1999 Dec;49(12):1039-43.

Density	1.2±0.1 g/cm3
Boiling Point	355.1±37.0 °C at 760 mmHg
Melting Point	80-84 °C(lit.)
Molecular Formula	C₁₀H₁₂O₄
Molecular Weight	196.200
Flash Point	141.2±20.0 °C
Exact Mass	196.073563
PSA	55.76000
LogP	2.37
Vapour Pressure	0.0±0.8 mmHg at 25°C
Index of Refraction	1.528

Xanthoxylin MSDS(Chinese)

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Risk Phrases	R36/37/38
Safety Phrases	S26-S36/37/39
RIDADR	NONH for all modes of transport
WGK Germany	3
HS Code	2914509090

Precursor 10
CAS#:480-66-0 2',4',6'-Trihyd... CAS#:77-78-1 Dimethyl sulfate CAS#:500-99-2 3,5-Dimethoxyphenol CAS#:75-36-5 Acetyl chloride
CAS#:832-58-6 2',4',6'-Trimet... CAS#:621-23-8 1,3,5-Trimethox... CAS#:2142-68-9 o-Chloroacetophenone CAS#:7087-68-5 DIEA
CAS#:80-48-8 Methyl p-toluen... CAS#:74-88-4 methyl iodide
DownStream 10
CAS#:10496-67-0 2''-HYDROXY-3,4... CAS#:10176-71-3 Ladanein CAS#:3420-72-2 Flavokawain A CAS#:480-66-0 2',4',6'-Trihyd...
CAS#:3602-54-8 2',4'-Dihydroxy... CAS#:491-70-3 Luteolin CAS#:5128-44-9 7,4'-Di-O-methy... CAS#:500-99-2 3,5-Dimethoxyphenol
CAS#:480-40-0 Chrysin CAS#:18064-89-6 1-(3-bromo-2-hy...

HS Code	2914509090
Summary	HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Collateral sensitivity of resistant MRP1-overexpressing cells to flavonoids and derivatives through GSH efflux.

Biochem. Pharmacol. 90(3) , 235-45, (2014)

The multidrug resistance protein 1 (MRP1) is involved in multidrug resistance of cancer cells by mediating drug efflux out of cells, often in co-transport with glutathione (GSH). GSH efflux mediated b...

Antinociceptive action of 2-(4-bromobenzoyl)-3-methyl-4,6-dimethoxy benzofuran, a novel xanthoxyline derivative on chemical and thermal models of nociception in mice.

J. Pharmacol. Exp. Ther. 278(1) , 304-12, (1996)

The antinociceptive effect of the novel xanthoxyline derivative 2-(4-bromobenzoyl)-3-methyl-4-6-dimethoxy benzofuran) (BMDB), given i.p., p.o., s.c., subplantarly, intrathecally or by i.c.v. routes wa...

Synthesis of chalcone analogues with increased antileishmanial activity.

Bioorg. Med. Chem. 14(5) , 1538-45, (2006)

Eighteen analogues of an active natural chalcone were synthesized using xanthoxyline and some derivatives, and these analogues were tested for selective activity against both promastigotes and intrace...

2-HYDROXY-4,6-DIMETHOXYACETOPHENONE

MFCD00017243

Brevifolin (VAN)

EINECS 201-978-3

4,6-Dimethoxy-2-hydroxyacetophenone

Phloracetophenone 4,6-Dimethyl Ether

2,4-Dimethoxy-6-hydroxyacetophenone

Acetophenone, 2'-hydroxy-4',6'-dimethoxy-

Ethanone, 1-(2-hydroxy-4,6-dimethoxyphenyl)-

1-(2-Hydroxy-4,6-dimethoxyphenyl)ethanone

BioBioPha
China
Product Name: Xanthoxylin
Price: ￥Inquiry/50mg
Purity: 98.0%
Stocking Period: 1 Day
Contact: Xueping-Zheng

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Xanthoxylin
Price: ￥378.0/1g ￥478.0/5mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Liu jia

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Ethanone,1-(2-hydroxy-4,6-dimethoxyphenyl)-
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Zhejiang Hangyu API Co., Ltd
China
Product Name: 2'-HYDROXY-4',6'-DIMETHOXYACETOPHENONE
Price: ￥Inquiry/1kg
Purity: 99.5%
Stocking Period: Inquiry
Contact: Vinnie

Henan Tianfu Chemical Co., Ltd.
China
Product Name: 2-Hydroxy-4,6-dimethoxyacetophenone
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

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Xanthoxylin

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