Timolol hemihydrate
Modify Date: 2025-08-22 11:29:15
Timolol hemihydrate structure
|
Common Name | Timolol hemihydrate | ||
|---|---|---|---|---|
| CAS Number | 91524-16-2 | Molecular Weight | 650.85500 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C26H50N8O7S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Timolol hemihydrateTimolol (hemihydrate) is a β-blocker available for both topical and systemic administration. Timolol (hemihydrate) is primarily used to reduce intraocular pressure with open-angle glaucoma and ocular hypertension and Timolol (hemihydrate) also has cardioprotective effect[1][2]. |
| Name | (S)-timolol hemihydrate |
|---|---|
| Synonym | More Synonyms |
| Description | Timolol (hemihydrate) is a β-blocker available for both topical and systemic administration. Timolol (hemihydrate) is primarily used to reduce intraocular pressure with open-angle glaucoma and ocular hypertension and Timolol (hemihydrate) also has cardioprotective effect[1][2]. |
|---|---|
| Related Catalog | |
| In Vitro | Timolol (hemihydrate) can significantly prevent the increased lipid peroxidation level of the heart from diabetic rats. Timolol (hemihydrate) can induce a well-balanced ratio between oxidative stress and antioxidant defense system in the diabetic animals, can have an important cardioprotection against diabetes-induced ERS and associated apoptotic effects[3]. |
| In Vivo | Timolol (hemihydrate) (5 mg/kg daily for 12-week) has a cardioprotective effect via inhibition of ERS response in diabetic rats[3]. Animal Model: Male Wistar rats[3]. Dosage: 5 mg/kg Administration: Timolol (5 mg/kg daily for 12-week) Result: Showed cardioprotective effect. |
| References |
| Molecular Formula | C26H50N8O7S2 |
|---|---|
| Molecular Weight | 650.85500 |
| Exact Mass | 650.32400 |
| PSA | 225.19000 |
| LogP | 1.85250 |
| timolol.0.5H2O |
| Timolol hemihydrate |
| (2S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol,hydrate |
| UNII-817W3C6175 |