Antiproliferative agent-15
Modify Date: 2024-04-06 15:25:14
Antiproliferative agent-15 structure
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Common Name | Antiproliferative agent-15 | ||
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| CAS Number | 19819-18-2 | Molecular Weight | 282.36000 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C16H14N2OS | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Antiproliferative agent-15Antiproliferative agent-15 is an anticancer agent. Antiproliferative agent-15 shows antiproliferative activity against human colon (HCT116 and HCT15) and brain (LN-229 and GBM-10) cancer cell lines[1]. |
| Name | 2-phenyl-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one |
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| Synonym | More Synonyms |
| Description | Antiproliferative agent-15 is an anticancer agent. Antiproliferative agent-15 shows antiproliferative activity against human colon (HCT116 and HCT15) and brain (LN-229 and GBM-10) cancer cell lines[1]. |
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| Related Catalog | |
| In Vitro | Antiproliferative agent-15 (compound 6a) shows antiproliferative activity against human colon (HCT116 and HCT15), brain (LN-229 and GBM-10) cancer cell lines, with IC50 values of 8.3 μM, 4.8 μM, 18.3 μM, and 12 μM, respectively. However, Antiproliferative agent-15 has no active against ovarian (A2780) cancer cell lines and normal cell line (CHO)[1]. |
| References |
| Molecular Formula | C16H14N2OS |
|---|---|
| Molecular Weight | 282.36000 |
| Exact Mass | 282.08300 |
| PSA | 74.25000 |
| LogP | 3.94270 |
| Vapour Pressure | 2.72E-07mmHg at 25°C |
| Storage condition | -20°C |
| 2-Phenyl-5,6,7,8-tetrahydro-3H-benzo[4,5]thieno[2,3-d]pyrimidin-4-one |
| 2-Phenyl-5,6,7,8-tetrahydro(1)benzothieno(2,3-d)pyrimidin-4(1H)-one |
| 2-phenyl-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one |
| (1)Benzothieno(2,3-d)pyrimidin-4(1H)-one,5,6,7,8-tetrahydro-2-phenyl |
| [1]benzothieno[2,3-d]pyrimidin-4(3h)-one,5,6,7,8-tetrahydro-2-phenyl |