methyl chloroacetate

Modify Date: 2024-01-02 09:54:01

methyl chloroacetate structure	Common Name	methyl chloroacetate
	CAS Number	96-34-4	Molecular Weight	108.524
	Density	1.2±0.1 g/cm3	Boiling Point	132.2±8.0 °C at 760 mmHg
	Molecular Formula	C₃H₅ClO₂	Melting Point	-33 °C
	MSDS	Chinese USA	Flash Point	51.7±0.0 °C
	Symbol	GHS02, GHS05, GHS06	Signal Word	Danger

Name	Methyl chloroacetate
Synonym	More Synonyms

Density	1.2±0.1 g/cm3
Boiling Point	132.2±8.0 °C at 760 mmHg
Melting Point	-33 °C
Molecular Formula	C₃H₅ClO₂
Molecular Weight	108.524
Flash Point	51.7±0.0 °C
Exact Mass	107.997810
PSA	26.30000
LogP	0.41
Vapour density	3.8 (vs air)
Vapour Pressure	9.0±0.2 mmHg at 25°C
Index of Refraction	1.401
Water Solubility	28 g/L (20 ºC)

methyl chloroacetate MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AF9500000

CHEMICAL NAME :: Acetic acid, chloro-, methyl ester

CAS REGISTRY NUMBER :: 96-34-4

LAST UPDATED :: 199710

DATA ITEMS CITED :: 9

MOLECULAR FORMULA :: C3-H5-Cl-O2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 250 ppm/7H

TOXIC EFFECTS :: Kidney, Ureter, Bladder - other changes Nutritional and Gross Metabolic - weight loss or decreased weight gain

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 19,1,1971

TYPE OF TEST :: LD16 - Lethal Dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 560 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,82,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 240 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,82,1982

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1 gm/m3/2H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,82,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - species unspecified

DOSE/DURATION :: 240 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 39(4),86,1974 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 5 mg/m3 JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4940 No. of Facilities: 22 (estimated) No. of Industries: 2 No. of Occupations: 2 No. of Employees: 1666 (estimated) No. of Female Employees: 272 (estimated)

Symbol	GHS02, GHS05, GHS06
Signal Word	Danger
Hazard Statements	H226-H301 + H331-H315-H318-H335
Precautionary Statements	P261-P280-P301 + P310-P305 + P351 + P338-P311
Personal Protective Equipment	Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	T:Toxic;
Risk Phrases	R10;R23/25;R37/38;R41
Safety Phrases	S26-S37/39-S45-S36-S16
RIDADR	UN 2295 6.1/PG 1
WGK Germany	2
RTECS	AF9500000
Packaging Group	I
Hazard Class	6.1
HS Code	2915400090

Precursor 10
CAS#:67-56-1 Methanol CAS#:79-11-8 Chloroacetic acid CAS#:6832-16-2 METHYL DIAZOACETATE CAS#:292638-85-8 acrylic acid me...
CAS#:77-78-1 Dimethyl sulfate CAS#:616-42-2 Dimethyl sulfite CAS#:79-07-2 2-Chloroacetamide CAS#:105-39-5 ethyl chloroacetate
CAS#:106865-88-7 CAS#:96-32-2 Methyl bromoacetate
DownStream 10
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CAS#:40967-67-7 Trimethyl 1,1,2... CAS#:5780-70-1 4-Methyl-1-pipe...

HS Code	2915400090
Summary	2915400090 mono-, di- or trichloroacetic acids, their salts and esters

Stable chlorine isotope analysis of chlorinated acetic acids using gas chromatography/quadrupole mass spectrometry.

Rapid Commun. Mass Spectrom. 29 , 2341-8, (2015)

The environmental occurrence of chlorinated acetic acids (CAAs) has been extensively studied, but the sources and transport are still not yet fully understood. A promising approach for source apportio...

Stopped-Flow Enantioselective HPLC-CD Analysis and TD-DFT Stereochemical Characterization of Methyl Trans-3-(3,4-Dimethoxyphenyl)Glycidate.

Chirality 27 , 914-8, (2015)

Caffeic acid-derived polyethers are a class of natural products isolated from the root extracts of comfrey and bugloss, which are endowed with intriguing pharmacological properties as anticancer agent...

Methyl chloroacetate as an extraction solvent for coupling liquid-liquid semimicroextraction with micellar electrokinetic chromatography through on-capillary decomposition for the separation of neutral compounds with concentration enhancement.

J. Chromatogr. A. 1147(1) , 105-10, (2007)

This paper reports the use of methyl chloroacetate (MCA) as an extraction solvent for coupling liquid-liquid semimicroextraction (LLsME) with micellar electrokinetic chromatography (MEKC) through on-c...

MFCD00000931

EINECS 202-501-1

methyl 2-chloroacetate