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L-2-氨基丁酸

L-2-氨基丁酸用途

H-Abu-OH 是氨基丁酸的三个同分异构体之一,其水平在患有雷氏综合征,酪氨酸血症,同型血尿症,非酮糖症以及鸟氨酸转氨酶症等代谢病儿童的血浆中会明显升高。

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L-2-氨基丁酸名称

[ CAS 号 ]:
1492-24-6

[ 中文名 ]:
L-2-氨基丁酸

[ 英文名 ]:
L(+)-2-Aminobutyric acid

[中文别名 ]:

[英文别名 ]:

α-Aminobutyric acid
(+)-2-Aminobutyric acid
(S)-2-Aminobutyrate
L(+)-2-Aminobutyric acid
Butanoic acid, 2-amino-, (2S)-
L-2-Aminobutyric Acid
L-α-aminobutyric acid
L-alpha-aminobutyric acid
Aminobutanoic acid
Butyric acid, 2-amino-, DL-

L-2-氨基丁酸生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 代谢疾病

天然产物 >> 其他

[ 靶点 ]

Human Endogenous Metabolite

[参考文献]

[1]. Yudkoff M, et al. On the clinical significance of the plasma alpha-amino-n-butyric acid:leucine ratio. Am J Clin Nutr. 1979 Feb;32(2):282-5.

[相关活性小分子]

L-2-氨基丁酸物理化学性质

[ 密度 ]:
1.2300

[ 沸点 ]:
215.2±23.0 °C at 760 mmHg

[ 熔点 ]:
300ºC

[ 分子式 ]:
C₄H₉NO₂

[ 分子量 ]:
103.120

[ 闪点 ]:
83.9±22.6 °C

[ 精确质量 ]:
103.063332

[ PSA ]:
63.32000

[ LogP ]:
-0.15

[ 外观性状 ]:
白色结晶固体

[ 蒸汽压 ]:
0.1±0.9 mmHg at 25°C

[ 折射率 ]:
1.462

[ 储存条件 ]:
room temp

[ 水溶解性 ]:
22.7 g/100 mL (22°C)

L-2-氨基丁酸MSDS

L-2-氨基丁酸安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H317

[ 警示性声明 ]:
P280

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ 危害码 (欧洲) ]:
Xi: Irritant;

[ 风险声明 (欧洲) ]:
R43

[ 安全声明 (欧洲) ]:
S36/37

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
2922499990

L-2-氨基丁酸合成路线

L-2-氨基丁酸上下游产品

L-2-氨基丁酸上游产品

L-2-氨基丁酸下游产品

L-2-氨基丁酸海关

[ 海关编码 ]: 2922499990

[ 中文概述 ]:
2922499990 其他氨基酸及其酯及它们的盐（含有一种以上含氧基的除外）. 增值税率:17.0% 退税率:9.0% 监管条件:AB(入境货物通关单,出境货物通关单) 最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

[ 监管条件 ]: A.入境货物通关单 B.出境货物通关单

[ 检验检疫 ]: P.进境动植物、动植物产品检疫 Q.出境动植物、动植物产品检疫 R.进口食品卫生监督检验 S.出口食品卫生监督检验 M.进口商品检验 N.出口商品检验

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

L-2-氨基丁酸文献

Urinary and plasma organic acids and amino acids in chronic fatigue syndrome.

Clin. Chim. Acta 361(1-2) , 150-8, (2005)

Previous work by others have suggested the occurrence of one or more chemical or metabolic 'markers' for ME/CFS including specific amino acids and organic acids and a number of unidentified compounds ...

Improving the serum D-xylose test for the identification of patients with small intestinal malabsorption.

J. Clin. Gastroenterol. 33(1) , 36-40, (2001)

D-Xylose absorption testing is a simple, low-cost method of screening for small intestinal malabsorption. The optimum method to measure D-xylose absorption (serum vs. urine testing) is uncertain.We pr...

Highly sensitive GC/MS/MS method for quantitation of amino and nonamino organic acids.

Anal. Chem. 83(7) , 2705-11, (2011)

Metabolite profiling methods are important tools for measurement of metabolite pools in biological systems. While most metabolite profiling methods report relative intensities or depend on a few inter...

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