阿扎哌隆
阿扎哌隆用途
阿扎哌隆名称
[ CAS 号 ]:
1649-18-9
[ 中文名 ]:
阿扎哌隆
[ 英文名 ]:
Azaperone
[中文别名 ]:
[英文别名 ]:
- Suicalm
- Stresnil
- Azaperon
- Azaperone
- Eucalmyl
- Sedaperone vet
- Fluoperidol
- EINECS 216-715-8
- MFCD00866692
- R-1929
阿扎哌隆生物活性
阿扎哌隆物理化学性质
[ 密度 ]:
1.2±0.1 g/cm3
[ 沸点 ]:
499.5±45.0 °C at 760 mmHg
[ 熔点 ]:
92-95ºC
[ 分子式 ]:
C19H22FN3O
[ 分子量 ]:
327.396
[ 闪点 ]:
255.9±28.7 °C
[ 精确质量 ]:
327.174683
[ PSA ]:
36.44000
[ LogP ]:
2.50
[ 外观性状 ]:
白色或灰白色结晶
[ 蒸汽压 ]:
0.0±1.3 mmHg at 25°C
[ 折射率 ]:
1.568
[ 储存条件 ]:
0-6°C
阿扎哌隆毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- EU4550000
- CHEMICAL NAME :
- Butyrophenone, 4'-fluoro-4-(4-(2-pyridyl)-1-piperazinyl)-
- CAS REGISTRY NUMBER :
- 1649-18-9
- BEILSTEIN REFERENCE NO. :
- 0565491
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 10
- MOLECULAR FORMULA :
- C19-H22-F-N3-O
- MOLECULAR WEIGHT :
- 327.44
- WISWESSER LINE NOTATION :
- T6N DNTJ D3VR DF& A- BT6NJ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 245 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - ptosis Behavioral - somnolence (general depressed activity) Behavioral - tremor
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 24,1798,1974
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 450 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - ptosis Behavioral - somnolence (general depressed activity) Behavioral - tremor
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 24,1798,1974
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 25 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,185,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 385 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - ptosis Behavioral - somnolence (general depressed activity) Behavioral - tremor
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 24,1798,1974
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 63 mg/kg
- TOXIC EFFECTS :
- Behavioral - changes in motor activity (specific assay) Behavioral - rigidity (including catalepsy)
- REFERENCE :
- FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 35,605,1980
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 179 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,185,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 42 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - ptosis Behavioral - somnolence (general depressed activity) Behavioral - tremor
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 24,1798,1974
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- >20 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - ptosis Behavioral - somnolence (general depressed activity) Gastrointestinal - nausea or vomiting
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 24,1798,1974
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- >40 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - ptosis Behavioral - somnolence (general depressed activity) Gastrointestinal - nausea or vomiting
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 24,1798,1974
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 202 mg/kg
- TOXIC EFFECTS :
- Behavioral - tremor Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 24,1798,1974
阿扎哌隆安全信息
[ 符号 ]:
GHS06
[ 信号词 ]:
Danger
[ 危害声明 ]:
H301
[ 警示性声明 ]:
Missing Phrase - N15.00950417
[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves
[ 危害码 (欧洲) ]:
Xn: Harmful;
[ 风险声明 (欧洲) ]:
R22
[ 危险品运输编码 ]:
UN2811 6.1/PG 3
[ RTECS号 ]:
EU4550000
[ 海关编码 ]:
2942000000
阿扎哌隆合成路线
阿扎哌隆上下游产品
阿扎哌隆上游产品
阿扎哌隆下游产品
阿扎哌隆海关
[ 海关编码 ]: 2933990090
[ 中文概述 ]:
2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6-己内酰胺请注明外观, 签约日期
[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
阿扎哌隆文献
J. Sci. Food Agric. 95(3) , 598-606, (2015)
The use of xenobiotic compounds in animal husbandry has given rise to consumer anxieties regarding residual risk and food safety. Thus, animal tissues have become main samples for residue analysis and...
Predominant leptospiral serogroups circulating among humans, livestock and wildlife in Katavi-Rukwa ecosystem, Tanzania.PLoS Negl. Trop. Dis. 9(3) , e0003607, (2015)
Leptospirosis is a worldwide zoonotic disease and a serious, under-reported public health problem, particularly in rural areas of Tanzania. In the Katavi-Rukwa ecosystem, humans, livestock and wildlif...
Simultaneous dermal matrix and autologous split-thickness skin graft transplantation in a porcine wound model: a three-dimensional histological analysis of revascularization.Wound Repair Regen. 22(6) , 749-54, (2015)
Despite the popularity of a simultaneous application of dermal matrices and split-thickness skin grafts, scarce evidence exists about the process of revascularization involved. In this study, we aimed...
相关化工产品/化学物质:
相关药品:
推荐生产厂家/供应商:
公司名:上海化源世纪贸易有限公司
区域:上海市普陀区
价格:
联系人:徐乾明
产品详情:1-(4-氟苯基)-4-(4-(吡啶-2-基)哌嗪-1-基)丁-1-酮
公司名:上海吉至生化科技有限公司
区域:上海市奉贤区
价格:
¥1478.0/100mg
¥6758.0/1g
联系人:刘佳
产品详情:阿扎哌隆
公司名:上海源溪生物科技有限公司
区域:上海市浦东新区
价格:
¥需询单/1g
联系人:赖经理
产品详情:Azaperone
公司名:上海脉铂医药科技有限公司
区域:上海市嘉定区
价格:
¥489.0/1g
¥489.0/50mg
¥需询单/1g
¥需询单/1g
联系人:李先生
产品详情:Azaperone
公司名:上海阿拉丁生化科技股份有限公司
区域:上海市浦东新区
价格:
¥164.9/100mg
¥706.9/1g
¥381.9/250mg
¥92.9/50mg
联系人:阿拉丁
产品详情:Azaperone
查看所有供应商请点击:
相关化合物
【阿扎哌隆】化源网提供阿扎哌隆CAS号1649-18-9,阿扎哌隆MSDS及其说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。CAS号查询阿扎哌隆上化源网,专业又轻松。>>电脑版:阿扎哌隆
标题:阿扎哌隆_用途_密度_熔点_阿扎哌隆CAS号【1649-18-9】_化源网 地址:https://m.chemsrc.com/mip/cas/1649-18-9_1026687.html