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辛卡利特

辛卡利特用途

Sincalide (INN) 是促胆囊收缩的药物,可以用作胆囊和胰腺疾病的研究。

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辛卡利特名称

[ CAS 号 ]:
25126-32-3

[ 中文名 ]:
辛卡利特

[ 英文名 ]:
Cholecystokinin Octapeptide (sulfated) ammonium salt

[中文别名 ]:

氯缩胆囊素八肽

[英文别名 ]:

Sincalide
CCK 26-33,SULFATED
Sincalide Acetate
MFCD00079849
CCK OCTAPEPTIDE SULFATED
CCKC-Terminal Octapeptide
cck-8
cholecystokinin octapeptide
cholecystokinin-26-33
Cholecystokinin C-terminal Octapeptide

辛卡利特生物活性

[ 描述 ]:

Sincalide (INN) 是促胆囊收缩的药物,可以用作胆囊和胰腺疾病的研究。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 癌症

多肽产品

[参考文献]

[1]. Maher KA et al. Kinevac (sincalide for injection)/Squibb Diagnostics. Gastroenterol Nurs. 1991 Oct;14(2):98-100.

[相关活性小分子]

辛卡利特物理化学性质

[ 密度 ]:
1.4±0.1 g/cm3

[ 分子式 ]:
C₄₉H₆₂N₁₀O₁₆S₃

[ 分子量 ]:
1143.269

[ 精确质量 ]:
1142.350708

[ PSA ]:
485.78000

[ LogP ]:
2.25

[ 折射率 ]:
1.643

[ 储存条件 ]:
-20°C

辛卡利特MSDS

详细MSDS(安全技术说明书)

辛卡利特安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 安全声明 (欧洲) ]:
S22-S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

辛卡利特合成路线

详细合成路线

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辛卡利特文献

Direct cellular delivery of human proteasomes to delay tau aggregation.

Nat. Commun. 5 , 5633, (2014)

The 26S proteasome is the primary machinery that degrades ubiquitin (Ub)-conjugated proteins, including many proteotoxic proteins implicated in neurodegeneraton. It has been suggested that the elevati...

The efficacy and mechanism of apoptosis induction by hypericin-mediated sonodynamic therapy in THP-1 macrophages.

Int. J. Nanomedicine 10 , 821-38, (2015)

To investigate the sonoactivity of hypericin (HY), together with its sonodynamic effect on THP-1 macrophages and the underlying mechanism.CCK-8 was used to examine cell viability. Confocal laser scann...

Aroclor 1254 inhibits cell viability and induces apoptosis of human A549 lung cancer cells by modulating the intracellular Ca(2+) level and ROS production through the mitochondrial pathway.

J. Environ. Sci. Health. A. Tox. Hazard. Subst. Environ. Eng. 50 , 806-13, (2015)

To study the acute toxic effects of PCBs on airway exposure, the cell viability, apoptosis and mitochondrial functions of human lung cancer cell line A549 were measured and compared after Aroclor 1254...

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