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6-羟基多巴胺盐酸盐

6-羟基多巴胺盐酸盐用途

Oxidopamine盐酸盐是一种人工合成的神经毒性有机化合物, 选择性地破坏大脑中多巴胺和去甲肾上腺素能神经元。

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6-羟基多巴胺盐酸盐名称

[ CAS 号 ]:
28094-15-7

[ 中文名 ]:
6-羟基多巴胺合氯化氢

[ 英文名 ]:
Oxidopamine hydrochloride

[中文别名 ]:

[英文别名 ]:

6-Hydroxydopamine hydrochloride
6-HYDROXYDOPAMINE HYDROCHLORIDE
5-(2-Aminoethyl)benzene-1,2,4-triol hydrochloride
Oxidopamine (hydrochloride)

6-羟基多巴胺盐酸盐生物活性

[ 描述 ]:

Oxidopamine盐酸盐是一种人工合成的神经毒性有机化合物, 选择性地破坏大脑中多巴胺和去甲肾上腺素能神经元。

[ 相关类别 ]:

信号通路 >> G 蛋白偶联受体/G 蛋白 >> 多巴胺受体

信号通路 >> 神经信号通路 >> 多巴胺受体

研究领域 >> 神经疾病

[相关活性小分子]

6-羟基多巴胺盐酸盐物理化学性质

[ 沸点 ]:
406ºC at 760 mmHg

[ 熔点 ]:
232-233ºC (dec.)(lit.)

[ 分子式 ]:
C₈H₁₂ClNO₃

[ 分子量 ]:
205.63900

[ 闪点 ]:
199.3ºC

[ 精确质量 ]:
205.05100

[ PSA ]:
86.71000

[ LogP ]:
1.80690

[ 蒸汽压 ]:
3.58E-07mmHg at 25°C

[ 储存条件 ]:
2-8℃

6-羟基多巴胺盐酸盐MSDS

详细MSDS(安全技术说明书)

6-羟基多巴胺盐酸盐毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DC4650000

CHEMICAL NAME :: 1,2,4-Benzenetriol, 5-(2-aminoethyl)-, hydrochloride

CAS REGISTRY NUMBER :: 28094-15-7

LAST UPDATED :: 199609

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C8-H11-N-O3.Cl-H

MOLECULAR WEIGHT :: 205.66

WISWESSER LINE NOTATION :: Z2R BQ CQ DQ &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 100 mg/kg/52W-I

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Liver - tumors Tumorigenic - tumors at site of application

REFERENCE :: RCOCB8 Research Communications in Chemical Pathology and Pharmacology. (PJD Pub. Ltd., P.O. Box 966, Westbury, NY 11590) V.1- 1970- Volume(issue)/page/year: 17,411,1977

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6-羟基多巴胺盐酸盐安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi: Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 危险品运输编码 ]:
NONH for all modes of transport

[ RTECS号 ]:
DC4650000

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