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DL-4-羟基苯乳酸

DL-4-羟基苯乳酸用途

Hydroxyphenyllactic acid 是一种抗真菌的代谢物。

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DL-4-羟基苯乳酸名称

[ CAS 号 ]:
306-23-0

[ 中文名 ]:
DL-4-羟基苯乳酸

[ 英文名 ]:
Hydroxyphenyllactic acid

[中文别名 ]:

3-(4-羟基苯基)乳酸

[英文别名 ]:

p-Hydroxyphenyl lactic acid
2-Hydroperoxy-2-phenylpropanoic acid
dl-p-Hydroxyphenyllactic acid
DL-4-Hydroxyphenyllactic Acid
3-(p-hydroxyphenyl)-D,L-lactic acid
4-Hydroxyphenyllactic acid
3-(4-hydroxyphenyl)-lactic acid
Benzeneacetic acid, α-hydroperoxy-α-methyl-
3-(4'-Hydroxyphenyl)-2-hydroxypropanoic acid
HPLA

DL-4-羟基苯乳酸生物活性

[ 描述 ]:

Hydroxyphenyllactic acid 是一种抗真菌的代谢物。

[ 相关类别 ]:

信号通路 >> 抗感染 >> 真菌

天然产物 >> 酸和醛

研究领域 >> 感染

[ 靶点 ]

Human Endogenous Metabolite

[体外研究]

羟基苯基乳酸(4-羟基苯基乳酸)是一种抗真菌代谢产物[1]。

[参考文献]

[1]. Mu W, et al. Production of 4-hydroxyphenyllactic acid by Lactobacillus sp. SK007 fermentation. J Biosci Bioeng. 2010 Apr;109(4):369-71.

[相关活性小分子]

DL-4-羟基苯乳酸物理化学性质

[ 密度 ]:
1.3±0.1 g/cm3

[ 沸点 ]:
370.0±35.0 °C at 760 mmHg

[ 分子式 ]:
C₉H₁₀O₄

[ 分子量 ]:
182.173

[ 闪点 ]:
152.5±19.4 °C

[ 精确质量 ]:
182.057907

[ PSA ]:
77.76000

[ LogP ]:
2.13

[ 外观性状 ]:
白色-几乎白色晶体-粉末固体

[ 蒸汽压 ]:
0.0±0.9 mmHg at 25°C

[ 折射率 ]:
1.563

[ 储存条件 ]:
室温

DL-4-羟基苯乳酸MSDS

详细MSDS(安全技术说明书)

DL-4-羟基苯乳酸毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: OD5500000

CHEMICAL NAME :: Lactic acid, 3-(p-hydroxyphenyl)-

CAS REGISTRY NUMBER :: 306-23-0

LAST UPDATED :: 199803

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C9-H10-O4

MOLECULAR WEIGHT :: 182.19

WISWESSER LINE NOTATION :: QVY1&OR DQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 800 mg/kg female 15-21 day(s) after conception

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Reproductive - Tumorigenic effects - transplacental tumorigenesis Lungs, Thorax, or Respiration - tumors

REFERENCE :: BEXBAN Bulletin of Experimental Biology and Medicine (English Translation). Translation of BEBMAE. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) V.41- 1956- Volume(issue)/page/year: 87,46,1979

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 800 mg/kg female 15-21 day(s) after conception

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Reproductive - Tumorigenic effects - transplacental tumorigenesis Blood - tumors

REFERENCE :: BEXBAN Bulletin of Experimental Biology and Medicine (English Translation). Translation of BEBMAE. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) V.41- 1956- Volume(issue)/page/year: 87,46,1979

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1600 mg/kg/8W-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Kidney, Ureter, Bladder - tumors

REFERENCE :: VOONAW Voprosy Onkologii. Problems of Oncology. For English translation, see PONCAU. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-10, 1928-37; V.1- 1955- Volume(issue)/page/year: 22(6),47,1976

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2800 mg/kg/10W-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Kidney, Ureter, Bladder - tumors Blood - leukemia

REFERENCE :: GETRE8 Gematologiya i Transfuziologiya. Hematology and Transfusion Science. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.28- 1983- Volume(issue)/page/year: 28(2),50,1983

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DL-4-羟基苯乳酸安全信息

[ 危害码 (欧洲) ]:
Xi: Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
26-36

[ 海关编码 ]:
2918290000

DL-4-羟基苯乳酸海关

[ 海关编码 ]: 2918290000

[ 中文概述 ]:
2918290000 其他含酚基但不含其他含氧基羧酸及其酸酐、酰卤化物、过氧化物和过氧酸及它们的衍生物。监管条件:AB(入境货物通关单,出境货物通关单)。增值税率:17.0%。退税率:9.0%。最惠国关税:6.5%。普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ 监管条件 ]: A.入境货物通关单 B.出境货物通关单

[ 检验检疫 ]: R.进口食品卫生监督检验 S.出口食品卫生监督检验

[ Summary ]:
HS: 2918290000 other carboxylic acids with phenol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) VAT:17.0% MFN tariff:6.5% General tariff:30.0%