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草乙酸

草乙酸用途

【用途一】
柠檬酸合成酶（citrate synthase）和苹果酸脱氢酶（malate dehydrogenase）的底物。也可作为琥珀酸脱氢酶的抑制剂。

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草乙酸名称

[ CAS 号 ]:
328-42-7

[ 中文名 ]:
草酰乙酸

[ 英文名 ]:
Oxaloacetic acid

[中文别名 ]:

[英文别名 ]:

cis-Oxaloacetic acid
OXALEACETIC ACID
Butanedioic acid, 2-oxo-
OXALOACETIC ACID
OAA
ketosuccinic acid
2-OXOSUCCINIC
MFCD00002592
EINECS 206-329-8
Oxobutanedioic acid

草乙酸物理化学性质

[ 密度 ]:
1.6±0.1 g/cm3

[ 沸点 ]:
341.9±25.0 °C at 760 mmHg

[ 熔点 ]:
161 °C (dec.)(lit.)

[ 分子式 ]:
C₄H₄O₅

[ 分子量 ]:
132.072

[ 闪点 ]:
174.8±19.7 °C

[ 精确质量 ]:
132.005875

[ PSA ]:
91.67000

[ LogP ]:
-1.60

[ 外观性状 ]:
灰白色晶体

[ 蒸汽压 ]:
0.0±1.6 mmHg at 25°C

[ 折射率 ]:
1.498

[ 储存条件 ]:
−20°C

[ 稳定性 ]:
Stable. Incompatible with strong oxidizing agents. Keep refrigerated.

[ 水溶解性 ]:
soluble

草乙酸MSDS

草乙酸安全信息

[ 符号 ]:

GHS05

[ 信号词 ]:
Danger

[ 危害声明 ]:
H314

[ 警示性声明 ]:
P280-P305 + P351 + P338-P310

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ 危害码 (欧洲) ]:
C:Corrosive;

[ 风险声明 (欧洲) ]:
R34

[ 安全声明 (欧洲) ]:
S26-S36/37/39-S45

[ 危险品运输编码 ]:
UN 3261 8/PG 2

[ WGK德国 ]:
3

[ 包装等级 ]:
II

[ 危险类别 ]:
8

[ 海关编码 ]:
2918300090

草乙酸合成路线

草乙酸上下游产品

草乙酸上游产品

草乙酸下游产品

草乙酸制备

可水解二乙基草酰乙酸钠盐与浓盐酸制得。

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草乙酸海关

[ 海关编码 ]: 2918300090

[ 中文概述 ]:
2918300090 其他含醛基或酮基不含其他含氧基羧酸（包括酸酐、酰卤化物、过氧化物和过氧酸及该税号的衍生物）. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

草乙酸文献

Intracellular flux analysis applied to the effect of dissolved oxygen on hybridomas.

Appl. Microbiol. Biotechnol. 44(1-2) , 27-36, (1995)

Quantitative estimates of intracellular fluxes and measurements of intracellular concentrations were used to evaluate the effect of dissolved oxygen (DO) concentration on CRL 1606 hybridoma cells in b...

The human cerebrospinal fluid metabolome

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 871(2) , 164-73, (2008)

With continuing improvements in analytical technology and an increased interest in comprehensive metabolic profiling of biofluids and tissues, there is a growing need to develop comprehensive referenc...

Quantitative measurement of organic acids in tissues from gastric cancer patients indicates increased glucose metabolism in gastric cancer.

PLoS ONE 9(6) , e98581, (2014)

The levels of organic acids representing metabolic pathway end products are important indicators of physiological status, and may be associated with metabolic changes in cancer. The aim of this study ...

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草乙酸