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氯丙酰苄胺

氯丙酰苄胺用途

Beclamide是一种药物, 具有抗惊厥活性, 已被用作镇静剂和作为抗惊厥药。

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氯丙酰苄胺名称

[ CAS 号 ]:
501-68-8

[ 中文名 ]:
氯丙酰苄胺

[ 英文名 ]:
Beclamide

[中文别名 ]:

贝克拉胺

[英文别名 ]:

Hibicon
3-Chlor-propionsaeure-benzylamid
Neuracen
3-Chlor-N-benzyl-propionamid
Chlorakon
Nidrane
Chloracon
Beclamide
3-chloro-propionic acid benzylamide
Posedrine

氯丙酰苄胺生物活性

[ 描述 ]:

Beclamide是一种药物, 具有抗惊厥活性, 已被用作镇静剂和作为抗惊厥药。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 神经疾病

[相关活性小分子]

氯丙酰苄胺物理化学性质

[ 密度 ]:
1.145g/cm3

[ 沸点 ]:
386.9ºC at 760mmHg

[ 分子式 ]:
C₁₀H₁₂ClNO

[ 分子量 ]:
197.66100

[ 闪点 ]:
187.8ºC

[ 精确质量 ]:
197.06100

[ PSA ]:
29.10000

[ LogP ]:
2.32260

[ 折射率 ]:
1.532

[ 储存条件 ]:
通风低温干燥

氯丙酰苄胺MSDS

详细MSDS(安全技术说明书)

氯丙酰苄胺毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UE3150000

CHEMICAL NAME :: Propionamide, N-benzyl-3-chloro-

CAS REGISTRY NUMBER :: 501-68-8

BEILSTEIN REFERENCE NO. :: 2720702

LAST UPDATED :: 199612

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C10-H12-Cl-N-O

MOLECULAR WEIGHT :: 197.68

WISWESSER LINE NOTATION :: G2VM1R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 107,403,1953

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 770 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 107,403,1953

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 770 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,384,1972

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1 gm/kg

TOXIC EFFECTS :: Behavioral - anticonvulsant

REFERENCE :: PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 14,99,1980

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 650 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,384,1972

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Mammal - species unspecified

DOSE/DURATION :: 1368 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 28,452,1994

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氯丙酰苄胺安全信息

[ 海关编码 ]:
2924299090

氯丙酰苄胺合成路线

详细合成路线

氯丙酰苄胺上下游产品

氯丙酰苄胺上游产品

氯丙酰苄胺下游产品

氯丙酰苄胺海关

[ 海关编码 ]: 2924299090

[ 中文概述 ]:
2924299090. 其他环酰胺（包括环氨基甲酸酯）（包括其衍生物以及他们的盐）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 包装

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%