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醋酸氟氢可的松

醋酸氟氢可的松用途

Fludrocortisone醋酸酯是一种合成的盐皮质激素, 用于治疗阿狄森氏病工作原理是减少尿液中钠丢失量, 也用于增加血压。

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醋酸氟氢可的松名称

[ CAS 号 ]:
514-36-3

[ 中文名 ]:
醋酸氟氢可的松

[ 英文名 ]:
Fludrocortisone acetate

[中文别名 ]:

[英文别名 ]:

Corticosterone, 9-fluoro-17-hydroxy-, 21-acetate
fludrocortisone 21-acetate
Alflorone
Cortisol, 9-fluoro-, 21-acetate
F-Cortef
Fludrocortisone acetate
EINECS 208-180-4
MFCD00864160
FLORINEF
Scherofluron

醋酸氟氢可的松生物活性

[ 描述 ]:

Fludrocortisone醋酸酯是一种合成的盐皮质激素, 用于治疗阿狄森氏病工作原理是减少尿液中钠丢失量, 也用于增加血压。

[ 相关类别 ]:

信号通路 >> 自噬 >> 自噬

信号通路 >> 代谢酶/蛋白酶 >> 盐皮质激素受体

研究领域 >> 炎症/免疫

[相关活性小分子]

醋酸氟氢可的松物理化学性质

[ 密度 ]:
1.3±0.1 g/cm3

[ 沸点 ]:
575.1±50.0 °C at 760 mmHg

[ 熔点 ]:
233-234°C

[ 分子式 ]:
C₂₃H₃₁FO₆

[ 分子量 ]:
422.487

[ 闪点 ]:
301.6±30.1 °C

[ 精确质量 ]:
422.210480

[ PSA ]:
100.90000

[ LogP ]:
2.32

[ 外观性状 ]:
结晶固体

[ 蒸汽压 ]:
0.0±3.6 mmHg at 25°C

[ 折射率 ]:
1.564

[ 储存条件 ]:
-20°C Freezer

醋酸氟氢可的松MSDS

详细MSDS(安全技术说明书)

醋酸氟氢可的松毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TU5050000

CHEMICAL NAME :: Pregn-4-ene-3,20-dione, 9-fluoro-11-beta,17,21-trihydroxy-, 21-acetate

CAS REGISTRY NUMBER :: 514-36-3

LAST UPDATED :: 199710

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C23-H31-F-O6

MOLECULAR WEIGHT :: 422.54

WISWESSER LINE NOTATION :: L E5 B666 OV MUTJ A1 BF CQ E1 FV1OV1 FQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 18,666,1987

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 240 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 18,666,1987

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醋酸氟氢可的松安全信息

[ 符号 ]:

GHS07, GHS08

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302-H361

[ 警示性声明 ]:
P280-P301 + P312 + P330

[ 危害码 (欧洲) ]:
Xn: Harmful;

[ 风险声明 (欧洲) ]:
R63

[ 安全声明 (欧洲) ]:
S22-S26-S36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
TU5050000

[ 海关编码 ]:
2937229000

醋酸氟氢可的松上下游产品

醋酸氟氢可的松上游产品

醋酸氟氢可的松下游产品

醋酸氟氢可的松海关

[ 海关编码 ]: 2937229000

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