< 生产厂家价格 >

枸橼酸沃克拉丁

枸橼酸沃克拉丁用途

Oxeladin柠檬酸盐是一种止咳剂, 有效治疗所有类型各种病因的咳嗽。

点击显示

枸橼酸沃克拉丁名称

[ CAS 号 ]:
52432-72-1

[ 中文名 ]:
枸橼酸沃克拉丁

[ 英文名 ]:
Oxeladin (citrate)

[英文别名 ]:

Bio-0361
HMS3264M05
Oxeladin citrate salt
oxeladin dihydrogen citrate
oxeladin citrate
Oxeladin-zitrat
Oxeladin (citrate)

枸橼酸沃克拉丁生物活性

[ 描述 ]:

Oxeladin柠檬酸盐是一种止咳剂, 有效治疗所有类型各种病因的咳嗽。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 炎症/免疫

[相关活性小分子]

枸橼酸沃克拉丁物理化学性质

[ 沸点 ]:
609.1ºC at 760 mmHg

[ 熔点 ]:
90-91°

[ 分子式 ]:
C₂₆H₄₁NO₁₀

[ 分子量 ]:
527.60400

[ 闪点 ]:
322.2ºC

[ 精确质量 ]:
527.27300

[ PSA ]:
170.90000

[ LogP ]:
2.39750

[ 外观性状 ]:
白色固体

[ 储存条件 ]:
-20℃

[ 水溶解性 ]:
Freely soluble in water, slightly to very slightly soluble in ethyl acetate.

枸橼酸沃克拉丁MSDS

详细MSDS(安全技术说明书)

枸橼酸沃克拉丁毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: ET1760000

CHEMICAL NAME :: Butyric acid, 2-ethyl-2-phenyl-, 2-(2-(diethylamino)ethoxy)ethyl ester, citrate

CAS REGISTRY NUMBER :: 52432-72-1

LAST UPDATED :: 198910

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C20-H33-N-O3.C6-H8-O7

MOLECULAR WEIGHT :: 527.68

WISWESSER LINE NOTATION :: 2X2&R&VO2O2N2&2 &QV1XQVQ1VQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 183 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,157,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 130 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,157,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 244 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold

REFERENCE :: YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 82,1314,1962

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 13 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,157,1982

点击显示

枸橼酸沃克拉丁安全信息

[ 符号 ]:

GHS06

[ 信号词 ]:
Danger

[ 危害声明 ]:
H301 + H311 + H331

[ 警示性声明 ]:
Missing Phrase - N15.00950417-P261-P280-P302 + P352 + P312-P304 + P340 + P312-P403 + P233

[ 个人防护装备 ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ 危害码 (欧洲) ]:
T

[ 风险声明 (欧洲) ]:
23/24/25

[ 安全声明 (欧洲) ]:
36/37/39-45

[ 危险品运输编码 ]:
UN 2811 6.1/PG 3

[ WGK德国 ]:
3

[ RTECS号 ]:
ET1760000

枸橼酸沃克拉丁文献

High performance liquid chromatographic determination of oxeladin citrate and oxybutynin hydrochloride and their degradation products.

Il Farmaco 60(8) , 689-99, (2005)

Two high performance liquid chromatographic (HPLC) methods are presented for the determination of oxeladin citrate (OL) and oxybutynin hydrochloride (OB) and their degradation products. The first meth...

Determination of oxeladin in human sera by gas--liquid chromatography with thermionic detection.

J. Chromatogr. A. 225(2) , 463-8, (1981)

[Determination of oxeladin citrate in drug combinations].

Pharmazie 37(1) , 76-7, (1982)

更多文献