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(+/-)-6-氯-7,8-二羟基-3-烯丙基-1-苯基-2,3,4,5-四氢-1H-3-苯氮杂卓氢溴酸

用途

SKF 82958是多巴胺D1/D5受体激动剂。

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名称

[ CAS 号 ]:
80751-65-1

[ 中文名 ]:
(+/-)-6-氯-7,8-二羟基-3-烯丙基-1-苯基-2,3,4,5-四氢-1H-3-苯氮杂卓氢溴酸

[ 英文名 ]:
SKF 82958

[英文别名 ]:

Cl-apb
(+/-)-CHLORO-APB HYDROBROMIDE
SKF 82958

生物活性

[ 描述 ]:

SKF 82958是多巴胺D1/D5受体激动剂。

[ 相关类别 ]:

信号通路 >> G 蛋白偶联受体/G 蛋白 >> 多巴胺受体

信号通路 >> 神经信号通路 >> 多巴胺受体

研究领域 >> 神经疾病

[参考文献]

[1]. Wang JQ, et al. The Full D1 Dopamine Receptor Agonist SKF-82958 Induces Neuropeptide mRNA in the Normosensitive Striatum of Rats: Regulation of D1/D2 Interactions by Muscarinic Receptors.J Pharmacol Exp Ther. 1997 May;281(2):972-82.

[相关活性小分子]

物理化学性质

[ 密度 ]:
1.234 g/cm3

[ 沸点 ]:
473.7ºC at 760 mmHg

[ 分子式 ]:
C₁₉H₂₀ClNO₂

[ 分子量 ]:
329.82

[ 闪点 ]:
240.3ºC

[ PSA ]:
43.70000

[ LogP ]:
4.82320

[ 外观性状 ]:
固体

[ 折射率 ]:
1.616

[ 储存条件 ]:
2-8℃

MSDS

详细MSDS(安全技术说明书)

安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

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