丙二酸二乙酯
丙二酸二乙酯结构式
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常用名 | 丙二酸二乙酯 | 英文名 | Diethyl malonate |
|---|---|---|---|---|
| CAS号 | 105-53-3 | 分子量 | 160.168 | |
| 密度 | 1.1±0.1 g/cm3 | 沸点 | 199.3±0.0 °C at 760 mmHg | |
| 分子式 | C7H12O4 | 熔点 | -50 °C | |
| MSDS | 中文版 美版 | 闪点 | 100.0±0.0 °C | |
| 符号 |
GHS07 |
信号词 | Warning |
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Design, synthesis and structure-activity relationship studies of novel and diverse cyclooxygenase-2 inhibitors as anti-inflammatory drugs.
J. Enzyme Inhib. Med. Chem. 29(6) , 846-67, (2014) Because of the pivotal role of cyclooxygenase (COX) in the inflammatory processes, non-steroidal anti-inflammatory drugs (NSAIDs) that suppress COX activities have been used clinically for the treatment of inflammatory diseases/syndromes; however, traditional... |
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Identification of olfactory receptor neurons in Uraba lugens (Lepidoptera: Nolidae) and its implications for host range.
J. Insect Physiol. 78 , 33-46, (2015) Phytophagous insects detect volatile compounds produced by host and non-host plants, using species-specific sets of olfactory receptor neurons (ORNs). To investigate the relationship between the range of host plants and the profile of ORNs, single sensillum r... |
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Ring expansion reactions of 4-amino-1,1-dioxo-[1,2,3,5]-thiatriazoles.
Org. Biomol. Chem. 5(3) , 472-7, (2007) An unusual ring-expansion reaction of 4-amino-1,1-dioxo-[1,2,3,5]-thiatriazoles has been identified that produces the relatively rare 5-amino-1,1-dioxo-[1,2,4,6]-thiatriazines and. Initial alkylation of the thiatriazole with alpha-halo-esters at N-3 produces ... |
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Intramolecular Hydrogen Bonding and Linear Pentapyrrole Conformation.
Monatsh. Chem 145(7) , 1117-1135, (2014) Three new linear pentapyrrole rubinoid analogs: 2,3,7,8,17,18,22,23-octamethyl-12,13-bis-(2-carboxyethyl)-1,10,15,24,25,27,28,29-octahydro-27H-pentapyrrin-1,24-dione and 2,3,8,12,13,17,22,23-octamethyl-7,18-bis-(2-carboxyethyl)-1,10,15,24,25,26,27,28,29-octah... |
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Room-temperature copper-catalyzed alpha-arylation of malonates.
Org. Lett. 9(17) , 3469-72, (2007) An effective method in targeting alpha-aryl malonates is reported. In the presence of a catalytic amount of 2-picolinic acid and CuI, the coupling of aryl iodides with diethyl malonate proceeds smoothly even at room temperature. The high levels of functional ... |
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Facility monitoring of chemical warfare agent simulants in air using an automated, field-deployable, miniature mass spectrometer.
Rapid Commun. Mass Spectrom. 25(10) , 1437-44, (2011) Vapors of four chemical warfare agent (CWA) stimulants, 2-chloroethyl ethyl sulfide (CEES), diethyl malonate (DEM), dimethyl methylphosphonate (DMMP), and methyl salicylate (MeS), were detected, identified, and quantitated using a fully automated, field-deplo... |
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Manganese(III)-catalyzed free radical reactions on trimetallic nitride endohedral metallofullerenes.
J. Am. Chem. Soc. 129(50) , 15710-7, (2007) The first reactions of trimetallic nitride templated endohedral metallofullerenes (TNT EMFs) with carbon radicals generated from diethyl malonate catalyzed by manganese(III) acetate are reported. Two methano monoadducts, Sc3N@C80-A and Sc3N@C80-B, were isolat... |
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Highly stereoselective, cobalt(III)-directed Mannich additions in water yielding α-methylamino acid products.
Dalton Trans. 42(1) , 292-8, (2013) Highly stereoselective and rapid (<1 min) addition reactions to the imine double bond of 2-(methylimino)acetate complexes [L(4)Co(O(2)CCH=NCH(3))](2+) [L(4) = (en)(2) (7), (tren) (11)] were achieved in aqueous solution with nitromethane, ethyl 3-oxobutanoate ... |
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Tandem Knoevenagel-Michael addition of aryl sulfonimines with diethyl malonate for synthesis of arylidene dimalonates.
J. Org. Chem. 72(15) , 5905-7, (2007) A highly efficient, one-flask tandem Knoevenagel-Michael addition reaction of sulfonimines with diethyl malonate in the presence of a catalytic amount of base affords the corresponding arylidene dimalonates in good to excellent yields. |
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Condensation of beta-diester titanium enolates with carbonyl substrates: a combined DFT and experimental investigation.
Chemistry 15(43) , 11537-50, (2009) The condensation of dialkyl beta-diesters with various aldehydes promoted by TiCl4 has been studied by DFT approaches and experimental methods, including NMR, IR and UV/Vis spectroscopy. Various possible reaction pathways have been investigated and their ener... |