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甲酰胺

甲酰胺结构式
甲酰胺结构式
品牌特惠专场
常用名 甲酰胺 英文名 Formamide
CAS号 75-12-7 分子量 45.041
密度 1.0±0.1 g/cm3 沸点 210.5±9.0 °C at 760 mmHg
分子式 CH3NO 熔点 2-3 °C(lit.)
MSDS 中文版 美版 闪点 81.1±18.7 °C
符号 GHS08
GHS08
信号词 Danger

RETRA exerts anticancer activity in Ewing's sarcoma cells independent of their TP53 status.

Eur. J. Cancer 51(7) , 841-51, (2015)

Mutant p53 can exert oncogenic activity by inhibitory interaction with p73. The small-molecule RETRA has been described to disrupt this interaction and to suppress carcinoma cells (Kravchenko et al., 2008). RETRA's anticancer activity was restricted to tumour...

Characterization of Pythium oligandrum populations that colonize the rhizosphere of vines from the Bordeaux region.

FEMS Microbiol. Ecol. 90(1) , 153-67, (2014)

This study focused on one oomycete, Pythium oligandrum, well-known for its plant protection abilities, which thrives in microbial environment where bacteria and fungal communities are also present. The genetic structures and dynamics of fungal and bacterial c...

Proper migration and axon outgrowth of zebrafish cranial motoneuron subpopulations require the cell adhesion molecule MDGA2A.

Biol. Open 4(2) , 146-54, (2015)

The formation of functional neuronal circuits relies on accurate migration and proper axonal outgrowth of neuronal precursors. On the route to their targets migrating cells and growing axons depend on both, directional information from neurotropic cues and ad...

Long-distance retinoid signaling in the zebra finch brain.

PLoS ONE 9(11) , e111722, (2014)

All-trans retinoic acid (ATRA), the main active metabolite of vitamin A, is a powerful signaling molecule that regulates large-scale morphogenetic processes during vertebrate embryonic development, but is also involved post-natally in regulating neural plasti...

Postmitotic control of sensory area specification during neocortical development.

Nat. Commun. 5 , 5632, (2014)

The mammalian neocortex is subdivided into cytoarchitectural areas with distinct connectivity, gene expression and neural functions. Areal identity is initially specified by rostrocaudal and mediolateral gene expression gradients in neuroepithelial and radial...

Early function of the Abutilon mosaic virus AC2 gene as a replication brake.

J. Virol. 89(7) , 3683-99, (2015)

The C2/AC2 genes of monopartite/bipartite geminiviruses of the genera Begomovirus and Curtovirus encode important pathogenicity factors with multiple functions described so far. A novel function of Abutilon mosaic virus (AbMV) AC2 as a replication brake is de...

Conversion of the LIMA1 tumour suppressor into an oncogenic LMO-like protein by API2-MALT1 in MALT lymphoma.

Nat. Commun. 6 , 5908, (2015)

MALT1 is the only known paracaspase and is a critical mediator of B- and T-cell receptor signalling. The function of the MALT1 gene is subverted by oncogenic chimeric fusions arising from the recurrent t(11;18)(q21;q21) aberration, which is the most frequent ...

Hyaluronic acid-functionalized single-walled carbon nanotubes as tumor-targeting MRI contrast agent.

Int. J. Nanomedicine 10 , 4507-20, (2015)

A tumor-targeting carrier, hyaluronic acid (HA)-functionalized single-walled carbon nanotubes (SWCNTs), was explored to deliver magnetic resonance imaging (MRI) contrast agents (CAs) targeting to the tumor cells specifically. In this system, HA surface modifi...

Clay catalyzed RNA synthesis under Martian conditions: Application for Mars return samples.

Biochem. Biophys. Res. Commun. 462 , 99-104, (2015)

Catalysis by montmorillonites clay minerals is regarded as a feasible mechanism for the abiotic production and polymerization of key biomolecules on early Earth. We have investigated a montmorillonite-catalyzed reaction of the 5'-phosphorimidazolide of nucleo...

Poly(A)-specific ribonuclease deficiency impacts telomere biology and causes dyskeratosis congenita.

J. Clin. Invest. 125 , 2151-60, (2015)

Dyskeratosis congenita (DC) and related syndromes are inherited, life-threatening bone marrow (BM) failure disorders, and approximately 40% of cases are currently uncharacterized at the genetic level. Here, using whole exome sequencing (WES), we have identifi...