24150-24-1

24150-24-1结构式

中文名	泰美普洛尔
英文名	meso-tetra-O-methyl nordihydroguaiaretic acid
英文别名	2,3-Dimethyl-1,4-bis-(3,4-dimethoxyphenyl)butane Teramrocol 4-[(2S,3R)-4-(3,4-dimethoxyphenyl)-2,3-dimethylbutyl]-1,2-dimethoxybenzene Meso-tetra-o-methylnordihydroguaietic acid Teramrocol, 10 mM in DMSO EM-1421 tetramethyl Nordihydroguaiaretic Acid Exclusive TETRAMETHYL NDGA TETRAMROCOL M4N inhibit,LOX,EM1421,EM 1421,Inhibitor,Lipoxygenase,Teramrocol Meso-tetramethoxy-4,4'-(2,3-dimethyltetramethylene)dipyrocatechol tetra-O-methyl-NDGA Tetra-O-methyl nordihydroguaietic acid TMNDGA TETRAMETHYL NORDIHYDROGUAIETIC ACID Benzene, 4-[(2R,3S)-4-(3,4-diMethoxyphenyl)-2,3-diMethylbutyl]-1,2-diMethoxy-, rel Butane, 1,4-bis(3,4-dimethoxyphenyl)-2,3-dimethyl-, meso 4-[(2R,3S)-4-(3,4-Dimethoxyphenyl)-2,3-dimethylbutyl]-1,2-dimethoxybenzene tetramethyl Nordihydroguaiaretic Acid rel-4-[(2R,3S)-4-(3,4-Dimethoxyphenyl)-2,3-dimethylbutyl]-1,2-dimethoxybenzene

描述	Terameprocol是去甲二氢愈创木酸的合成衍生物,是一种非选择性脂氧合酶抑制剂。Terameprocol具有抗病毒和抗肿瘤作用[1][2][3]。
相关类别	研究领域 >> 癌症研究领域 >> 感染信号通路 >> 代谢酶/蛋白酶 >> 5脂氧合酶
参考文献	[1]. Hwu JR, et al. Antiviral activities of methylated nordihydroguaiaretic acids. 1. Synthesis, structure identification, and inhibition of tat-regulated HIV transactivation. J Med Chem. 1998 Jul 30;41(16):2994-3000. [2]. Chen H, et al. Antiviral activities of methylated nordihydroguaiaretic acids. 2. Targeting herpes simplex virus replication by the mutation insensitive transcription inhibitor tetra-O-methyl-NDGA. J Med Chem. 1998 Jul 30;41(16):3001-7. [3]. Park R, et al. Systemic treatment with tetra-O-methyl nordihydroguaiaretic acid suppresses the growth of human xenograft tumors. Clin Cancer Res. 2005 Jun 15;11(12):4601-9.