培哚普利

• 常用名: 培哚普利
• 英文名: Perindopril erbumine
• CAS号: 107133-36-8
• 分子量: 441.605
• 密度: 1.15 g/cm3
• 沸点: 537.4ºC at 760mmHg
• 分子式: C₂₃H₄₃N₃O₅
• 熔点: 126-128ºC
• 闪点: 278.8ºC

培哚普利用途

【用途1】
用于治疗高血压、充血性心力衰竭等病症

培哚普利名称

• 中文名: 培哚普利叔丁胺盐
• 英文名: perindopril erbumine
• 中文别名: 培哚 | 培哚普利

培哚普利生物活性

• 描述: Perindopril是长效血管紧张素转换酶(ACE)抑制剂。
• 相关类别:
  信号通路 >> 代谢酶/蛋白酶 >> 血管紧张素转换酶(ACE)
  研究领域 >> 心血管疾病
• 参考文献:

  [1]. Vaclavik J, Perindopril in the treatment of hypertension and cardiovascular diseases: evolution continues with the orodispersible dosage form. Vnitr Lek. 2013 Apr;59(4):290-4.

  [2]. Napalkov DA. Therapy with perindopril: organoprotection, not just the antihypertensive effect. Kardiologiia. 2012;52(12):80-3.

培哚普利物理化学性质

• 密度: 1.15 g/cm3
• 沸点: 537.4ºC at 760mmHg
• 熔点: 126-128ºC
• 分子式: C₂₃H₄₃N₃O₅
• 分子量: 441.605
• 闪点: 278.8ºC
• 精确质量: 441.320282
• PSA: 121.96000
• LogP: 3.71330
• InChIKey: IYNMDWMQHSMDDE-MHXJNQAMSA-N
• SMILES: CC(C)(C)N.CCCC(NC(C)C(=O)N1C(C(=O)O)CC2CCCCC21)C(=O)OCC
• 外观性状: 白色固体
• 储存条件: -20°C Freezer
• 水溶解性: H2O: soluble10mg/mL, clear

培哚普利安全信息

• 个人防护装备: Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
• 危害码 (欧洲): Xi
• 风险声明 (欧洲): R36/37/38
• 安全声明 (欧洲): 26-36
• 危险品运输编码: NONH for all modes of transport
• RTECS号: NL5999600

培哚普利靶点实验

查看更多实验

实验名称：ERK5 transcriptional activity HTS 来源：24565 靶标：N/A External Id：ERK5 transcriptional activity-HTS

实验名称：Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: lu... 来源：824 External Id：CYP273

实验名称：A screen for compounds that inhibit the activity of LtaS in Staphylococcus aureus 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School External Id：HMS979

实验名称：Identifying Sarm1 Tir Hydrolase inhibitors through NAD-Glo assay 来源：24386 靶标：N/A External Id：Sarm1 Tir NADase inhibitors screen

实验名称：Increase the activity of the Burkholderia fixLJ 2-component system 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：Burkholderia multivorans External Id：HMS1625

实验名称：qHTS assay to identify small molecule agonists of the TGF-beta/Smad signaling pathway... 来源：824 靶标：N/A External Id：TGF788

实验名称：qHTS assay to identify small molecule antagonists of the TGF-beta/Smad signaling path... 来源：824 靶标：N/A External Id：TGF602

实验名称：p53 small molecule agonists, cell-based qHTS assay: qHTS cell viability counter scree... 来源：824 靶标：N/A External Id：P53600

实验名称：p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: qHTS ce... 来源：824 靶标：N/A External Id：P53MS958

实验名称：p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: Summary 来源：824 External Id：P53MS482

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培哚普利英文别名

• Aceon
• S 9490-3
• PrestariuM
• (2S,3aS,7aS)-1-[(2S)-2-{[(1S)-1-(ethoxycarbonyl)butyl]amino}propanoyl]octahydro-1H-indole-2-carboxylic acid - 2-methylpropan-2-amine (1:1) (non-preferred name)
• (2S,3aS,7aS)-1-[(2S)-2-{[(2S)-1-Ethoxy-1-oxopentan-2-yl]amino}propanoyl]octahydro-1H-indole-2-carboxylic acid - 2-methylpropan-2-amine (1:1) (non-preferred name)
• acide (2S,3aS,7aS)-1-[(2S)-2-{[(1S)-1-(éthoxycarbonyl)butyl]amino}propanoyl]octahydro-1H-indole-2-carboxylique - 2-méthylpropan-2-amine (1:1)
• McN-A 2833-109
• McN-A-2833-109
• Perinodpril ErbiMune
• ButylaMiniperindopril
• Perindoril
• Perindopril erbumine
• MFCD02313824
• Perindopril tert-butylamine
• (2S,3aS,7aS)-1-[(2S)-2-{[(2S)-1-Ethoxy-1-oxo-2-pentanyl]amino}propanoyl]octahydro-1H-indole-2-carboxylic acid - 2-methyl-2-propanamine (1:1)
• S-9490-3
• Perindopril t-Butylamine Salt
• (2S,3aS,7aS)-1-((S)-N-((S)-1-Carboxybutyl)alanyl)hexahydro-2-indolinecarboxylic Acid 1-Ethyl Ester compound with tert-Butylamine (1:1)
• Procaptan
• Unii-1964X464oj
• Coversyl
• (2S,3aS,7aS)-1-[(2S)-2-{[(1S)-1-(Ethoxycarbonyl)butyl]amino}propanoyl]octahydro-1H-indol-2-carbonsäure--2-methylpropan-2-amin(1:1)
• (2S-(1(R*(R*)),2a,3ab,7ab))-1-(2-((1-(Ethoxycarbonyl)butyl)amino)-1-oxopropyl)octahydro-1H-indole-2-carboxylic Acid compd. with 2-Methyl-2-propanamine (1:1)
• Perinodopril
• Coversum
• (2S,3aS,7aS)-1-[(2S)-2-{[(1S)-1-(ethoxycarbonyl)butyl]amino}propanoyl]octahydro-1H-indole-2-carboxylic acid - 2-methylpropan-2-amine (1:1)
• Perindopril t-Butylamine