柳穿鱼黄素

• 常用名: 柳穿鱼黄素
• 英文名: Pectolinarigenin
• CAS号: 520-12-7
• 分子量: 314.289
• 密度: 1.4±0.1 g/cm3
• 沸点: 565.5±50.0 °C at 760 mmHg
• 分子式: C₁₇H₁₄O₆
• 熔点: 220-223°
• 闪点: 212.3±23.6 °C

柳穿鱼黄素用途

Pectolinarigenin 可从 Cirsium chanroenicum 中分离,是 COX-2/5-LOX 的双重抑制剂。具有抗炎活性。Pectolinarigenin 对黑素生成具有有效的抑制作用。

柳穿鱼黄素名称

• 中文名: 柳穿鱼黄素
• 英文名: pectolinarigenin

柳穿鱼黄素生物活性

• 描述: Pectolinarigenin 可从 Cirsium chanroenicum 中分离,是 COX-2/5-LOX 的双重抑制剂。具有抗炎活性。Pectolinarigenin 对黑素生成具有有效的抑制作用。
• 相关类别:
  研究领域 >> 炎症/免疫
  信号通路 >> 免疫及炎症 >> COX
  信号通路 >> 代谢酶/蛋白酶 >> 5脂氧合酶
• 靶点实验:

  COX-2

  5-LOX

• 参考文献:

  [1]. Lim H, et al. Anti-inflammatory activity of pectolinarigenin and pectolinarin isolated from Cirsium chanroenicum. Biol Pharm Bull. 2008 Nov;31(11):2063-7.

  [2]. Lee S, et al. Pectolinarigenin, an aglycone of pectolinarin, has more potent inhibitory activities on melanogenesis than pectolinarin.Biochem Biophys Res Commun. 2017 Nov 4;493(1):765-772.

柳穿鱼黄素物理化学性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 565.5±50.0 °C at 760 mmHg
• 熔点: 220-223°
• 分子式: C₁₇H₁₄O₆
• 分子量: 314.289
• 闪点: 212.3±23.6 °C
• 精确质量: 314.079041
• PSA: 89.13000
• LogP: 2.64
• 蒸汽压: 0.0±1.6 mmHg at 25°C
• 折射率: 1.646
• 储存条件: 2-8C

柳穿鱼黄素安全信息

• 安全声明 (欧洲): 24/25
• 海关编码: 2914509090

柳穿鱼黄素海关

• 海关编码: 2914509090
• 中文概述: 2914509090 含其他含氧基的酮. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:5.5% 普通关税:30.0%
• 申报要素: 品名, 成分含量, 用途, 丙酮报明包装
• Summary: HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

柳穿鱼黄素靶点实验

查看更多实验

实验名称：Luminescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：mu-type opioid receptor isoform MOR-1 [Homo sapiens] External Id：OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_AG_FLUO8_1536_1X%ACT PRUN

实验名称：Immunosuppressive activity in human Jurkat cells assessed as reduction in PHA + PMA-i... 来源：ChEMBL 靶标：Jurkat External Id：CHEMBL4311817

实验名称：Cytotoxicity against human PC9 cells after 72 hrs by MTT assay 来源：ChEMBL 靶标：PC-9 External Id：CHEMBL4311815

实验名称：Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay 来源：ChEMBL 靶标：HepG2 External Id：CHEMBL4311814

实验名称：Cytotoxicity against human NCI-H1975 cells after 72 hrs by MTT assay 来源：ChEMBL 靶标：NCI-H1975 External Id：CHEMBL4311813

实验名称：Inhibition of AChE (unknown origin) at 250 uM using acetylthiocholine iodide as subst... 来源：ChEMBL 靶标：Acetylcholinesterase External Id：CHEMBL4311824

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify pos... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_PAM_FLUO8_1536_1X%ACT PRUN

实验名称：Inhibition of cow milk xanthine oxidase at 50 ug/mL 来源：ChEMBL 靶标：Xanthine dehydrogenase/oxidase External Id：CHEMBL1015630

实验名称：Anti-inflammatory activity in mouse RAW264.7 cells assessed as reduction in LPS-induc... 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL4311822

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柳穿鱼黄素英文别名

• 4'-Methylcapillarisin
• 5,7-Dihydroxy-6-methoxy-2-(4-methoxyphenyl)-4H-chromen-4-one
• 6-Hydroxypelargidenon-6,4'-dimethyl Ether
• 6-Methoxyacacetin
• 5,7-dihydroxy-6,4'-dimethoxyflavone
• 5,7-dihydroxy-6-methoxy-2-(4-methoxyphenyl)chromen-4-one
• pictolinarigenin
• scutellarein-6,4'-dimethyl ether
• Pectolinarigenin
• Pectolinaringenin
• 5,7-Dihydroxy-6-methoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one
• 5,7-dihydroxy-4',6-dimethoxyflavone