Axl-IN-8 structure
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Common Name | Axl-IN-8 | ||
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CAS Number | 2231424-62-5 | Molecular Weight | 552.60 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C31H29FN6O3 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of Axl-IN-8Axl-IN-8 (NO.1) is a potent AXL inhibitor, with an IC50 of <1 nM. Axl-IN-8 also inhibits c-MET, with an IC50 of 1-10 nM. Axl-IN-8 shows anti-proliferative activity against BaF3/TEL-AXL, MKN45, and EBC-1 cells, with IC50 values of <10, 226.6 and 120.3 nM, respectively[1]. |
Name | Axl-IN-8 |
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Description | Axl-IN-8 (NO.1) is a potent AXL inhibitor, with an IC50 of <1 nM. Axl-IN-8 also inhibits c-MET, with an IC50 of 1-10 nM. Axl-IN-8 shows anti-proliferative activity against BaF3/TEL-AXL, MKN45, and EBC-1 cells, with IC50 values of <10, 226.6 and 120.3 nM, respectively[1]. |
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Related Catalog | |
Target |
c-Met:1-10 nM (IC50) |
References |
Molecular Formula | C31H29FN6O3 |
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Molecular Weight | 552.60 |