ALK5-IN-28
Modify Date: 2023-06-12 20:11:20
ALK5-IN-28 structure
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Common Name | ALK5-IN-28 | ||
|---|---|---|---|---|
| CAS Number | 2785430-84-2 | Molecular Weight | 425.53 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C25H27N7 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of ALK5-IN-28ALK5-IN-28 (compound Ex-05) is a selective ALK-5 inhibitor (IC50≤10 nM), inhibits TGF-β-induced SMAD signaling. ALK5-IN-28 has the potential to inhibit growth of tumour in vivo. ALK5-IN-28 can be used in study of proliferative diseases such as cancer, fibrotic diseases, and systemic sclerosis[1]. |
| Name | ALK5-IN-28 |
|---|
| Description | ALK5-IN-28 (compound Ex-05) is a selective ALK-5 inhibitor (IC50≤10 nM), inhibits TGF-β-induced SMAD signaling. ALK5-IN-28 has the potential to inhibit growth of tumour in vivo. ALK5-IN-28 can be used in study of proliferative diseases such as cancer, fibrotic diseases, and systemic sclerosis[1]. |
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| Related Catalog | |
| Target |
ALK5:≤10 nM (IC50) |
| References |
[1]. Bettina FRANZ, et al. Alk-5 inhibitors and uses thereof. Patent WO2022126133A1. |
| Molecular Formula | C25H27N7 |
|---|---|
| Molecular Weight | 425.53 |