1426152-53-5

1426152-53-5 structure

Name: UNC 2327
Chemical Name: UNC2327
CAS Number: 1426152-53-5
Molecular Formula: C₁₄H₁₇N₅O₂S
Molecular Weight: 319.382
Create Date: 2021-01-07 15:54:44
Modify Date: 2025-08-26 12:39:54
UNC2327 is an allosteric inhibitor of protein arginine methyltransferase 3 (PRMT3).

Name	UNC2327
Synonyms	UNC2327 Urea, N-1,2,3-benzothiadiazol-6-yl-N'-[2-oxo-2-(1-piperidinyl)ethyl]- 1-(1,2,3-Benzothiadiazol-6-yl)-3-[2-oxo-2-(1-piperidinyl)ethyl]urea

Description	UNC2327 is an allosteric inhibitor of protein arginine methyltransferase 3 (PRMT3).
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Epigenetics >> Histone Methyltransferase
Target	PRMT3
References	[1]. Liu F, et al. Exploiting an allosteric binding site of PRMT3 yields potent and selective inhibitors. J Med Chem. 2013 Mar 14;56(5):2110-24.