Antiproliferative agent-6

Modify Date: 2024-01-10 18:43:45

Antiproliferative agent-6 Structure
Antiproliferative agent-6 structure
Common Name Antiproliferative agent-6
CAS Number 2389016-82-2 Molecular Weight 404.83
Density N/A Boiling Point N/A
Molecular Formula C21H14ClFN6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Antiproliferative agent-6


Antiproliferative against-6 (compound 8a) is a potent antitumor agent. Antiproliferative against-6 has antiproliferative activity against cancer cell lines HCT116, MCF-7, H460 and non-tumor aneuploid immortal keratinocyte HaCaT cells with GI50s of 0.5 μM, 2 μM, 0.7 μM and 3.5 μM, respectively[1].

 Names

Name Antiproliferative agent-6

 Antiproliferative agent-6 Biological Activity

Description Antiproliferative against-6 (compound 8a) is a potent antitumor agent. Antiproliferative against-6 has antiproliferative activity against cancer cell lines HCT116, MCF-7, H460 and non-tumor aneuploid immortal keratinocyte HaCaT cells with GI50s of 0.5 μM, 2 μM, 0.7 μM and 3.5 μM, respectively[1].
Related Catalog
Target

GI50: 0.5 μM (HCT116), 2 μM (MCF-7), 0.7 μM (H460), 3.5 μM (HaCaT)[1]

References

[1]. Meščić Macan A, et al. Synthesis, antiproliferative activity and DNA/RNA-binding properties of mono- and bis-(1,2,3-triazolyl)-appended benzimidazo[1,2-a]quinoline derivatives. Eur J Med Chem. 2020;185:111845.

 Chemical & Physical Properties

Molecular Formula C21H14ClFN6
Molecular Weight 404.83