tert-Butyl (2-(2-(2-hydroxyethoxy)ethoxy)ethyl)carbamate

Modify Date: 2024-01-02 12:39:03

tert-Butyl (2-(2-(2-hydroxyethoxy)ethoxy)ethyl)carbamate structure	Common Name	tert-Butyl (2-(2-(2-hydroxyethoxy)ethoxy)ethyl)carbamate
	CAS Number	139115-92-7	Molecular Weight	249.30400
	Density	1.071g/cm3	Boiling Point	374.6ºC at 760 mmHg
	Molecular Formula	C₁₁H₂₃NO₅	Melting Point	N/A
	MSDS	N/A	Flash Point	180.3ºC

Use of tert-Butyl (2-(2-(2-hydroxyethoxy)ethoxy)ethyl)carbamate

PROTAC Linker 10 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 10 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Name	2-[2-(2-t-Boc-aminoethoxy]ethoxy]ethanol
Synonym	More Synonyms

Description	PROTAC Linker 10 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 10 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	Alkyl/ether
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Density	1.071g/cm3
Boiling Point	374.6ºC at 760 mmHg
Molecular Formula	C₁₁H₂₃NO₅
Molecular Weight	249.30400
Flash Point	180.3ºC
Exact Mass	249.15800
PSA	77.02000
LogP	0.92750
Vapour Pressure	3.84E-07mmHg at 25°C
Index of Refraction	1.456
Storage condition	2-8°C

Hazard Codes	Xi
HS Code	2924199090

Precursor 7
CAS#:6338-55-2 2-[2-(2-Aminoet... CAS#:24424-99-5 Di-tert-butyl d... CAS#:86520-52-7 Azido-PEG3-alcohol CAS#:112-27-6 Triethylene glycol
CAS#:86770-70-9 ((2-(2-(2-Azido... CAS#:77544-68-4 Tos-PEG3 CAS#:5197-62-6 2-(2-(2-Chloroe...
DownStream 4
CAS#:153086-78-3 N-BOC-2,2′-(eth... CAS#:166388-57-4 Azido-PEG2-C2-amine CAS#:139338-72-0 Fmoc-amino-PEG3... CAS#:189209-27-6 PROTAC Linker 17

HS Code	2924199090
Summary	2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%