N-Methylguanine
Modify Date: 2024-01-10 21:09:57
N-Methylguanine structure
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Common Name | N-Methylguanine | ||
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| CAS Number | 10030-78-1 | Molecular Weight | 165.153 | |
| Density | 1.8±0.1 g/cm3 | Boiling Point | 488.2ºC at 760mmHg | |
| Molecular Formula | C6H7N5O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 249.1ºC | |
Use of N-MethylguanineN2-Methylguanine is a modified nucleoside. N2-Methylguanine is an endogenous methylated nucleoside found in human fluids. |
| Name | 2-(methylamino)-3,7-dihydropurin-6-one |
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| Synonym | More Synonyms |
| Description | N2-Methylguanine is a modified nucleoside. N2-Methylguanine is an endogenous methylated nucleoside found in human fluids. |
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| Related Catalog | |
| Target |
Human Endogenous Metabolite |
| In Vitro | N2-methylguanine is found within both helical and looped regions of RNA secondary structure, and it can exist in either the s-cis or the s-trans rotamer. If there is a rotational preference for the methyl group, the effect of N2-methylguanine substitution may be specific to the sequence context depending upon which face of the base participates in hydrogen bonding[1]. N2-methylguanine is the principal kinetic barrier for reverse transcription in the 1340 bases proximal to the 5' end of E. coli 16S rRNA. Transcription intermediates correspond to attenuation at the positions of N2-methylguanine in the rRNA sequence. The relaxation time for elongation of the cDNA through m2G is approximately 3 min[2]. |
| References |
| Density | 1.8±0.1 g/cm3 |
|---|---|
| Boiling Point | 488.2ºC at 760mmHg |
| Molecular Formula | C6H7N5O |
| Molecular Weight | 165.153 |
| Flash Point | 249.1ºC |
| Exact Mass | 165.065063 |
| PSA | 86.72000 |
| LogP | -1.85 |
| Vapour Pressure | 0.00389mmHg at 25°C |
| Index of Refraction | 1.848 |
| Hazard Codes | Xi |
|---|---|
| HS Code | 2933990090 |
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N-Methylguanine CAS#:10030-78-1 |
| Literature: Journal of the American Chemical Society, , vol. 78, p. 217,219 |
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N-Methylguanine CAS#:10030-78-1 |
| Literature: Chemistry of Heterocyclic Compounds, , vol. 32, # 3 p. 338 - 341 |
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N-Methylguanine CAS#:10030-78-1 |
| Literature: Journal of the American Chemical Society, , vol. 78, p. 217,219 |
CAS#:2140-77-4| HS Code | 2933990090 |
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| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
| 2-(Methylamino)-1,7-dihydro-6H-purin-6-one |
| 6-Hydroxy-2-methylaminopurine |
| 2-Monomethylamino-6-hydroxypurine |
| 2-(Methylamino)-1H-purin-6(7H)-one |
| Guanine,N-methyl |
| N-Methylguanine |
| Purine,6-hydroxy-2-methylamino |
| 2-Methylamino-1,9-dihydro-purin-6-one |
| 2-Methylguanine |
| 2-Methylamino-6-oxopurine |
| N2-Methylguanine |
| 2-methylamino-1,7-dihydro-purin-6-one |
| N(2)-methylguanine |
| 6H-Purin-6-one, 1,7-dihydro-2-(methylamino)- |