Bis-Mal-PEG3

Modify Date: 2024-01-09 17:45:50

Bis-Mal-PEG3 Structure
Bis-Mal-PEG3 structure
Common Name Bis-Mal-PEG3
CAS Number 1008402-47-8 Molecular Weight 494.495
Density 1.3±0.1 g/cm3 Boiling Point 791.7±60.0 °C at 760 mmHg
Molecular Formula C22H30N4O9 Melting Point N/A
MSDS N/A Flash Point 432.6±32.9 °C

 Use of Bis-Mal-PEG3


Bis-Mal-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name N,N'-[Oxybis(2,1-ethanediyloxy-2,1-ethanediyl)]bis[3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamide]
Synonym More Synonyms

 Bis-Mal-PEG3 Biological Activity

Description Bis-Mal-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 791.7±60.0 °C at 760 mmHg
Molecular Formula C22H30N4O9
Molecular Weight 494.495
Flash Point 432.6±32.9 °C
Exact Mass 494.201294
LogP -2.61
Vapour Pressure 0.0±2.8 mmHg at 25°C
Index of Refraction 1.549

 Synonyms

N,N'-[Oxybis(2,1-ethanediyloxy-2,1-ethanediyl)]bis[3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamide]
1H-Pyrrole-1-propanamide, N,N'-[oxybis(2,1-ethanediyloxy-2,1-ethanediyl)]bis[2,5-dihydro-2,5-dioxo-
Top Suppliers:I want be here
  • DC Chemicals Limited
  • China
  • Product Name: Bis-Mal-PEG3
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao


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