MLS-573151
Modify Date: 2024-02-03 16:08:45
MLS-573151 structure
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Common Name | MLS-573151 | ||
|---|---|---|---|---|
| CAS Number | 10179-57-4 | Molecular Weight | 377.460 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 596.3±60.0 °C at 760 mmHg | |
| Molecular Formula | C21H19N3O2S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 314.5±32.9 °C | |
Use of MLS-573151MLS-573151 (MLS000573151) is a selective GTPase Cdc42 inhibitor with an EC50 of 2 μM. MLS-573151 is inactive against other GTPases family members, such as Rab2, Rab7, H-Ras, Rac1, Rac 2 and RhoA wild-type. MLS-573151 acts by blocking the binding of GTP to Cdc42[1][2]. |
| Name | 4-(3,5-Diphenyl-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide |
|---|---|
| Synonym | More Synonyms |
| Description | MLS-573151 (MLS000573151) is a selective GTPase Cdc42 inhibitor with an EC50 of 2 μM. MLS-573151 is inactive against other GTPases family members, such as Rab2, Rab7, H-Ras, Rac1, Rac 2 and RhoA wild-type. MLS-573151 acts by blocking the binding of GTP to Cdc42[1][2]. |
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| Related Catalog | |
| In Vitro | The fluorescence intensities of phagocytosed beads or bacteria in hemocytes, taken as a measure of phagocytosis efficiency, were markedly reduced in granulocytes treated with MLS-573151 (50 μM; for 15 min) compared to that in the control group. MLS-573151 could effectively inhibit the phagocytic ability of granulocytes[1]. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 596.3±60.0 °C at 760 mmHg |
| Molecular Formula | C21H19N3O2S |
| Molecular Weight | 377.460 |
| Flash Point | 314.5±32.9 °C |
| Exact Mass | 377.119812 |
| PSA | 84.14000 |
| LogP | 1.90 |
| Vapour Pressure | 0.0±1.7 mmHg at 25°C |
| Index of Refraction | 1.669 |
|
~71%
MLS-573151 CAS#:10179-57-4 |
| Literature: Feid-Allah Pharmazie, 1981 , vol. 36, # 11 p. 754 - 756 |
| 4-(3,5-Diphenyl-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide |
| 1-<4-Pyrrolidinomethyl-phenyl>-2-phenyl-6-methoxy-3,4-dihydronaphthalin-hydrochlorid |
| Benzenesulfonamide, 4-(4,5-dihydro-3,5-diphenyl-1H-pyrazol-1-yl)- |
| MLS-573151 |