Xanthine oxidoreductase-IN-4
Modify Date: 2024-04-07 00:32:32
Xanthine oxidoreductase-IN-4 structure
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Common Name | Xanthine oxidoreductase-IN-4 | ||
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| CAS Number | 1026587-58-5 | Molecular Weight | 309.32 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C16H15N5O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Xanthine oxidoreductase-IN-4Xanthine oxidoreductase-IN-4 is an orally active xanthine oxidoreductase (XOR) inhibitor. Xanthine oxidoreductase-IN-4 has inhibitory activity against XOR with an IC50 value of 29.3 nM. Xanthine oxidoreductase-IN-4 can be used for the research of hyperuricemia[1]. |
| Name | Xanthine oxidoreductase-IN-4 |
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| Description | Xanthine oxidoreductase-IN-4 is an orally active xanthine oxidoreductase (XOR) inhibitor. Xanthine oxidoreductase-IN-4 has inhibitory activity against XOR with an IC50 value of 29.3 nM. Xanthine oxidoreductase-IN-4 can be used for the research of hyperuricemia[1]. |
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| Related Catalog | |
| Target |
IC50: 29.3 nM (XOR)[1] |
| In Vitro | Xanthine oxidoreductase-IN-4 (Compound IIIc) 对 XOR 具有抑制活性，IC50 值为 29.3 nM[1]。 |
| In Vivo | Xanthine oxidoreductase-IN-4 (Compound IIIc) (oral; 5 mg/kg)在恶嗪酸钾/次黄嘌呤诱导的急性高尿酸血症模型中显示出显着的低尿酸血症效应[1]。 Animal Model: Mice acute hyperuricemia model[1] Dosage: 5 mg/kg Administration: Oral Result: Reduced serum levels of uric acid significantly from 4 h after administration. |
| References |
| Molecular Formula | C16H15N5O2 |
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| Molecular Weight | 309.32 |